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Lung cancer, also known as lung carcinoma, is a malignant tumor that begins in the lung. Lung cancer is caused by genetic damage to the DNA of cells in the airways, often caused by cigarette smoking or inhaling damaging chemicals. Damaged airway cells gain the ability to multiply unchecked, causing the growth of a tumor.
Lung cancer staging is the assessment of the extent to which a lung cancer has spread from its original source. As with most cancers, staging is an important determinant of treatment and prognosis. In general, more advanced stages of cancer are less amenable to treatment and have a worse prognosis.
The Journal of Thoracic Oncology is a peer-reviewed medical journal covering research into cancer of the thorax, especially lung cancer.It was established in 2006 and is published nine times per year by Elsevier on behalf of the International Association for the Study of Lung Cancer, of which it is the official journal.
Thoracic radiotherapy generally begins with the first or second cycle when chemotherapy is used according to most guidelines. [19] The time between the start and the end of chemoradiotherapy is a predicator of survival in limited stage small cell lung cancer, prolongation leads to a decrease in overall survival of 1.9% per week. [20]
While lung cancer is the deadliest cancer, a stigma surrounds the disease that it is highly preventable by not smoking. [82] Lung cancer receives much less press time then other cancers such as breast cancer due to this stigma, with a survey of 1,000 participants finding that only 14% of those participants were the most concerned about lung ...
After full staging, the NSCLC patient can typically be classified in one of three different categories: patients with early, nonmetastatic disease (stages I and II, and select type III tumors), patients with locally advanced disease confined to the thoracic cavity (e.g., large tumors, tumors involving critical chest structures, or patients with ...
The signs and symptoms of this specific type of lung cancer are similar to other forms of lung cancer, and patients most commonly complain of persistent cough and shortness of breath. Adenocarcinoma is more common in patients with a history of cigarette smoking, and is the most common form of lung cancer in younger women and Asian populations.
The most recent 2015 World Health Organization (WHO) and 2011 International Association for the Study of Lung Cancer (IASLC) / American Thoracic Society (ATS) guidelines refine pulmonary adenocarcinoma subtypes in order to correspond to advances in personalized cancer treatment. [2]