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Bronchiectasis without CF is known as non-CF bronchiectasis. Historically, about half of all cases of non-CF bronchiectasis were found to be idiopathic, or without a known cause. [25] However, more recent studies with a more thorough diagnostic work-up have found an etiology in 60 to 90% of patients. [24] [26] [27]
Obstructive lung disease is a category of respiratory disease characterized by airway obstruction.Many obstructive diseases of the lung result from narrowing (obstruction) of the smaller bronchi and larger bronchioles, often because of excessive contraction of the smooth muscle itself.
In February 2014, the US FDA granted an orphan drug designation to doxofylline for the treatment of bronchiectasis following the submission of an application by Alitair Pharmaceuticals, in May 2013. [ 6 ] [ 7 ] [ 8 ]
The Impact of Bronchial Artery Embolization on the Quality of Life of Patients with Haemoptysis: A Prospective Observational Study - The study quantitatively demonstrated the mental anguish of patients with hemoptysis and the relief provided by BAE, indicating an improvement in both physical and particularly mental QOL after BAE. Omachi N ...
The package leaflet supplied with the product is aimed at end-users. [3] A cartoon by Roy Doty depicting the package insert as overly long and complicated. In the United States, the Food and Drug Administration (FDA) determines the requirements for patient package inserts.
Chronic obstructive pulmonary disease (COPD) is a type of progressive lung disease characterized by chronic respiratory symptoms and airflow limitation. [8] GOLD 2024 defined COPD as a heterogeneous lung condition characterized by chronic respiratory symptoms (dyspnea or shortness of breath, cough, sputum production or exacerbations) due to abnormalities of the airways (bronchitis ...
Other causes of similar symptoms include asthma, pneumonia, bronchiolitis, bronchiectasis, and COPD. [2] [4] A chest X-ray may be useful to detect pneumonia. [4] Another common sign of bronchitis is a cough lasting ten days to three weeks. If the cough lasts longer than a month, it may become chronic bronchitis. In addition, a fever may be present.
During the study 467 patients with moderate-to-severe stable COPD were randomized and treated in 47 hospital-based pulmonary clinics in 10 European countries. After 1 year of treatment there was a 1.4% reduction in the exacerbation rate with erdosteine treatment; this result was mainly driven by the reduction in the rate of mid exacerbations ...