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Furosemide (Lasix) for injection. Furosemide is primarily used for the treatment of edema , but also in some cases of hypertension (where there is also kidney or heart impairment). [ 14 ] It is often viewed as a first-line agent in most people with edema caused by congestive heart failure because of its anti-vasoconstrictor and diuretic effects.
It is given by injection into a vein. [2] Side effects may include irritation of the vein in which it is given, high blood sugar, and swelling. [2] [3] Excess use may result in low blood sodium and other electrolyte problems. [2] Intravenous sugar solutions are in the crystalloid family of medications. [4]
Water for injection is generally made by distillation or reverse osmosis. [5] It should contain less than a mg of elements other than water per 100 ml. [5] Versions with agents that stop bacterial growth are also available. [5] In the UK, some hospitals offer subcutaneous injections of water directly for treating back pain in labour.
Mannitol lowers the intra cranial pressure through two effects in the brain. The first, rheological effect, reduces blood viscosity, and promotes plasma expansion and cerebral oxygen delivery. In response, cerebral vasoconstriction occurs due to autoregulation, and cerebral blood volume is decreased. The second effect occurs through creation of ...
Triamterene – increased renal side-effects; Aldosterone antagonists, also known as mineralocorticoid receptor antagonists: [7] Spironolactone – most widespread use, inexpensive; Eplerenone – more selective so reduced side-effects but more expensive and less potent
Generally, the strength of the formulation for injection into a vein should not be greater than 40 mmol/L (3 mg/L). [4] Potassium chloride came into large scale commercial use as a fertilizer in 1861 and has been used medically since the 1950s. [6] [7] It is on the World Health Organization's List of Essential Medicines. [8]
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Metolazone and a loop diuretic will synergistically enhance diuresis over the use of either agent alone. Using this combination, diuretic effects will occur at two different segments of the nephron; namely, the loop diuretic will act at the loop of Henle, and metolazone will act at the distal convoluted tubule. Metolazone is frequently ...
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