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Alcohol flush reaction; Other names: Asian flush syndrome, Asian flush reaction, Asian glow, Asian red face glow: Facial flushing. Before (left) and after (right) drinking alcohol. A 22-year-old East Asian man who is ALDH2 heterozygous showing the reaction. [1] Specialty: Toxicology: Frequency: 36% of East Asians [2] [1] [3]
Alcohol intolerance is due to a genetic polymorphism of the aldehyde dehydrogenase enzyme, which is responsible for the metabolism of acetaldehyde (produced from the metabolism of alcohol by alcohol dehydrogenase). [1] [2] This polymorphism is most often reported in patients of East Asian descent.
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Alcohol-induced asthma reactions among Asians has been most thoroughly studied in those of native Japanese descent. In such individuals, the ingestion of virtually any alcoholic beverage or pure ethanol and, in some cases, the smelling of ethanol fumes may be followed, typically within 1–30 minutes, by one or more of the following symptoms: an alcohol flush reaction (i.e. the "Asian flush ...
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Koob says research suggests that earlier alcohol use is associated with a higher likelihood of developing alcohol use disorder, even when the alcohol is provided by an adult at home; and kids ...
Alcohol flush reaction is a condition in which an individual's face or body experiences flushes (appears red) or blotches as a result of an accumulation of acetaldehyde, a metabolic byproduct of the catabolic metabolism of alcohol. It is best known as a condition that is experienced by people of Asian descent.
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