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Finally, the characteristics and the duration of a patient's symptoms should be analyzed. The onset of symptoms during or close after chemotherapy is generally described as affecting sensation in the feet first, then in the hands and fingers. [1] If a patient experiences such abnormalities in sensation, then CIPN should be suspected.
Diabetes most commonly causes damage to the long nerves that supply the feet and lower legs, causing numbness, tingling and pain (diabetic polyneuropathy). Although these symptoms may also be present, the pain and weakness of proximal diabetic neuropathy often onset more quickly and affect nerves closer to the torso. [citation needed]
Diabetes is the leading known cause of neuropathy in developed countries, and neuropathy is the most common complication and greatest source of morbidity and mortality in diabetes. A systematic review has found that diabetic peripheral neuropathy affects 30% of diabetes patients. [1]
The causes range from physical inactive and eating the wrong foods to the body simply not producing insulin. And Melissa Joy Dobbins , a certified diabetes educator, says that it certainly doesn't ...
Undiagnosed and unmanaged diabetes may increase the risk of nerve fiber damage in the body, including in the hands and feet. That can feel like itchiness, sensitivity to temperature, numbness, and ...
Peripheral neuropathy may be classified according to the number and distribution of nerves affected (mononeuropathy, mononeuritis multiplex, or polyneuropathy), the type of nerve fiber predominantly affected (motor, sensory, autonomic), or the process affecting the nerves; e.g., inflammation (), compression (compression neuropathy), chemotherapy (chemotherapy-induced peripheral neuropathy).
However, diabetes does cause higher morbidity, mortality and operative risks with these conditions. [41] Diabetic foot, often due to a combination of sensory neuropathy (numbness or insensitivity) and vascular damage, increases rates of skin ulcers (diabetic foot ulcers) and infection and, in serious cases, necrosis and gangrene. It is why it ...
Nerve decompressions are associated with a significant reduction in pain, in some cases the complete elimination of pain. [64] [58] [59] For patients with diabetic peripehral neuropathy (which affects 30% of diabetes patients [65]) and superimposed nerve compression, this may be treatable with multiple nerve decompressions.