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CIPN afflicts between 30% and 40% of patients undergoing chemotherapy. Antineoplastic agents in chemotherapy are designed to eliminate rapidly dividing cancer cells, but they can also damage healthy structures, including the peripheral nervous system. [1] CIPN involves various symptoms such as tingling, pain, and numbness in the hands and feet. [2]
Peripheral neuropathy may be classified according to the number and distribution of nerves affected (mononeuropathy, mononeuritis multiplex, or polyneuropathy), the type of nerve fiber predominantly affected (motor, sensory, autonomic), or the process affecting the nerves; e.g., inflammation (), compression (compression neuropathy), chemotherapy (chemotherapy-induced peripheral neuropathy).
Diabetes is the leading known cause of neuropathy in developed countries, and neuropathy is the most common complication and greatest source of morbidity and mortality in diabetes. A systematic review has found that diabetic peripheral neuropathy affects 30% of diabetes patients. [1]
Chronically high blood sugar levels in patients with advanced diabetes can lead to nerve and blood vessel damage. It could also cause diabetic retinopathy or peripheral neuropathy. Diabetic ...
Endocrinologists share uncommon symptoms of diabetes that may indicate type 1, type 2, or prediabetes. Some signs include infections and dry skin.
Some common causes of autonomic neuropathy include: Diabetes, which is the most common cause of autonomic neuropathy, can gradually cause nerve damage throughout the body. Injury to nerves caused by surgery or radiation to the neck. Treatment with certain medications, including some drugs used in cancer chemotherapy.
Dysesthesia is among symptoms of neuropathy (along with paresthesias, gait disturbance, weakness, and absent DTRs). Dysesthesia, along with polyneuropathy can be a symptom of nerve damage caused by Lyme disease. [4] The dysesthetic sensations continue after the successful antibiotic treatment of Lyme disease.
Blood clots are a medical emergency in their own right—and can lead to heart attack and stroke—so if you notice these changes, seek treatment right away, she urges. Jaw or neck pain with exertion