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Nail fungus can be painful and cause permanent damage to nails. It may lead to other serious infections if the immune system is suppressed due to medication, diabetes or other conditions. The risk is most serious for people with diabetes and with immune systems weakened by leukemia or AIDS, or medication after organ transplant.
This condition may follow certain diseases such as syphilis, or can result from fever, trauma, systemic upsets or adverse reaction to drugs. Onychorrhexis also known as brittle nails, is brittleness with breakage of fingernails or toenails. Paronychia is a bacterial or fungal infection where the nail and skin meet.
A common misconception is that the cause of an ingrown toenail is the nail growing into the paronychium, but it can also be caused by overgrown toe skin. [2] The condition is caused by a microbial inflammation of the paronychium causing a granuloma within which the nail is buried. [3]
And sometimes what looks like toenail fungus is actually a different animal altogether, Del Campo notes: The skin condition psoriasis, for example, sometimes appears in the nails first.
Trichophyton rubrum is a dermatophytic fungus in the phylum Ascomycota.It is an exclusively clonal, [2] anthropophilic saprotroph that colonizes the upper layers of dead skin, and is the most common cause of athlete's foot, fungal infection of nail, jock itch, and ringworm worldwide. [3]
[9] [10] These bacteria do not normally survive on dry, healthy skin, but can thrive in moist conditions. [9] The seal between the nail and finger acts as a physical barrier to prevent infection, however hyper-hydration or destruction of the epidermis can impair the barrier, allowing the bacteria to colonise.
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