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With finasteride blocking 5-alpha-reductase, less testosterone is converted into DHT, meaning you’ll have more testosterone in your system. But this rise in testosterone doesn’t last forever.
The 5-alpha reductase blockers like finasteride reduce DHT levels and slow down, stop or reverse the effects of male pattern baldness. They can also encourage hair regrowth and increase hair count.
Finasteride is a 5α-reductase inhibitor and therefore an antiandrogen. [10] It works by decreasing the production of dihydrotestosterone (DHT) by about 70%. [6] In addition to DHT, finasteride also inhibits the production of several anticonvulsant neurosteroids including allopregnanolone, androstanediol, and tetrahydrodeoxycorticosterone. [11]
Research has shown that finasteride cuts DHT levels in the prostate by upwards of 90 percent, and in the bloodstream by more than 70 percent. ... groups and treated with finasteride. The men in ...
Some studies show it can reduce DHT but doesn’t help with hair growth. Other studies show that topical finasteride is as effective as oral finasteride after 18 months of treatment.
[6] [7] It decreases circulating DHT levels by up to about 70%. [8] Dutasteride (brand name Avodart) inhibits all three 5α-reductase isoenzymes and can decrease DHT levels by 95%. [9] [10] It can also reduce DHT levels in the prostate by 97 to 99% in men with prostate cancer.
By blocking DHT production directly at the source, finasteride drastically reduces the levels of DHT in your body. Research shows that it can lower the amount of DHT by as much as 70 percent.
Finasteride Blocks DHT to Stop Hair Loss. Finasteride is one of two 5-alpha reductase inhibitors, along with dutasteride. 5-alpha reductase is an enzyme that your body eventually converts into a ...
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