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Doty has published over 400 papers in peer-reviewed journals related to olfactory and gustatory function, [citation needed] and is the editor or author of nine books, including Handbook of Olfaction and Gustation, [3] Neurology of Olfaction with Christopher Hawkes, [4] and The Great Pheromone Myth, [5] among others.
The Lady and the Unicorn, a Flemish tapestry depicting the sense of smell, 1484–1500. Musée national du Moyen Âge, Paris.. Early scientific study of the sense of smell includes the extensive doctoral dissertation of Eleanor Gamble, published in 1898, which compared olfactory to other stimulus modalities, and implied that smell had a lower intensity discrimination.
The olfactory system, is the sensory system used for the sense of smell (olfaction). Olfaction is one of the special senses directly associated with specific organs. Most mammals and reptiles have a main olfactory system and an accessory olfactory system. The main olfactory system detects airborne substances, while the accessory system senses ...
Olfactory stimulation was provided to the subjects with different aromatic air samples with a 5-second rest period, followed by a 20-second olfactory stimulus period. It was concluded that the odor of lemon, traditionally thought to be stimulative, had the effect of activating anticipation or attention process.
The vibration theory of smell proposes that a molecule's smell character is due to its vibrational frequency in the infrared range. This controversial theory is an alternative to the more widely accepted docking theory of olfaction (formerly termed the shape theory of olfaction), which proposes that a molecule's smell character is due to a range of weak non-covalent interactions between its ...
Glomeruli are important waystations in the pathway from the nose to the olfactory cortex and have been found to be critical for odorant signal transduction. The olfactory receptor neurons (ORN), which originate in the nasal epithelium express only one type of olfactory receptor (OR). These ORNs then project their axons to the olfactory bulb.
The accessory olfactory bulb resides on the dorsal-posterior region of the main olfactory bulb and forms a parallel pathway. Destruction of the olfactory bulb results in ipsilateral anosmia, while irritative lesions of the uncus can result in olfactory and gustatory hallucinations. Flow of olfactory information from receptors to glomeruli layer
The AON is found behind the olfactory bulb and in front of the piriform cortex (laterally) and olfactory tubercle (medially) in the olfactory tract (also olfactory peduncle) or retrobulbar area. [5] [6] The peduncle contains the AON as well as two other much smaller regions, the ventral and dorsal tenia tecta.