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The gestational sac is spherical in shape, and is usually located in the upper part (fundus) of the uterus.By approximately nine weeks of gestational age, due to folding of the trilaminar germ disc, the amniotic sac expands and occupy the majority of the volume of the gestational sac, eventually reducing the extraembryonic coelom (the gestational sac or the chorionic cavity) to a thin layer ...
The amniotic sac, also called the bag of waters [1] [2] or the membranes, [3] is the sac in which the embryo and later fetus develops in amniotes. It is a thin but tough transparent pair of membranes that hold a developing embryo (and later fetus) until shortly before birth .
The inner cell mass will give rise to the pre-embryo, [9] the amnion, yolk sac and allantois, while the fetal part of the placenta will form from the outer trophoblast layer. The embryo plus its membranes is called the conceptus , and by this stage the conceptus has reached the uterus .
Fetal heart tone (the sound of the heart beat) can be heard using doppler. Nipples and hair follicles begin to form. Location of the elbows and toes are visible. Spontaneous limb movements may be detected by ultrasound. All essential organs have at least begun. The vitelline duct normally closes.
Gestational sac size, location, and number; Identification of the embryo and/or yolk sac; Measurement of fetal length (known as the crown-rump length) Fetal number, including number of amnionic sacs and chorionic sacs for multiple gestations; Embryonic/fetal cardiac activity; Assessment of embryonic/fetal anatomy appropriate for the first trimester
The fetal membranes separate maternal tissue from fetal tissue at a basic mechanical level. The fetal membrane is composed of a thick cellular chorion covering a thin amnion composed of dense collagen fibrils. The amnion is in contact with the amniotic fluid and ensures structural integrity of the sac due to its mechanical strength.
The vasoconstriction of the effects of cocaine lead to a decrease in placental blood flow to the fetus that results in fetal hypoxia (oxygen deficiency) and decreased fetal nutrition; these vasoconstrictive effects on the placenta have been linked to the number of complications in malformations that are evident in the newborn. [42]
Absence of embryo with heartbeat 7–10 days after a scan that showed a gestational sac with a yolk sac. [110] [111] Absence of embryo at least 6 weeks after last menstrual period. [110] [111] Amniotic sac seen adjacent to yolk sac, and with no visible embryo. [110] [111] Yolk sac of more than 7 mm. [110] [111]
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