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  2. Spironolactone - Wikipedia

    en.wikipedia.org/wiki/Spironolactone

    [141] [198] [199] [200] However, although very high doses of spironolactone can considerably decrease steroid hormone levels in animals, spironolactone has shown mixed and inconsistent effects on steroid hormone levels in clinical studies, even at high clinical doses.

  3. Pharmacodynamics of spironolactone - Wikipedia

    en.wikipedia.org/wiki/Pharmacodynamics_of...

    Spironolactone has shown no significant effect on levels of testosterone, estradiol, luteinizing hormone, and follicle-stimulating hormone in men. [ 146 ] [ 78 ] No or only small changes in cortisol levels have been observed in clinical studies with spironolactone.

  4. Yes, Experts Explain You Can Still Lose Weight If You Have PCOS

    www.aol.com/yes-experts-explain-still-lose...

    And because PCOS affects many hormones (example: estrogen) that are responsible for a variety of bodily functions, women with PCOS may also find it hard to become pregnant. ... and spironolactone ...

  5. Mineralocorticoid receptor antagonist - Wikipedia

    en.wikipedia.org/wiki/Mineralocorticoid_receptor...

    Eplerenone is a newer drug that was developed as a spironolactone analog with reduced adverse effects. In addition to the y-lactone ring and the substituent on C-7, eplerenone has a 9α,11α-epoxy group. This group is believed to be the reason why eplerenone has a 20-40-fold lower affinity for the mineralocorticoid receptor than spironolactone. [7]

  6. Androgenetic Alopecia: Everything to Know About Male ... - AOL

    www.aol.com/androgenetic-alopecia-everything...

    Androgenetic alopecia is caused by a combination of factors including genetic predisposition and the effects of male sex hormones called androgens. ... other medications like spironolactone may be ...

  7. Everything You Need to Know About Acne, from Causes to ... - AOL

    www.aol.com/everything-know-acne-causes...

    Spironolactone reduces the amount of androgen hormones in your body, which cuts down sebum production. Its effects on hormones are so pronounced that it is not recommended for treating acne in men ...

  8. Spirolactone - Wikipedia

    en.wikipedia.org/wiki/Spirolactone

    Spirolactones are a class of functional group in organic chemistry featuring a cyclic ester attached spiro to another ring system. The name is also used to refer to a class of synthetic steroids, called steroid-17α-spirolactones, 17α-spirolactosteroids, or simply 17α-spirolactones, which feature their spirolactone group at the C17α position.

  9. 10 Hormones That Affect Weight & How to Reset Them - AOL

    www.aol.com/lifestyle/10-hormones-affect-weight...

    Hormones can be helpful heroes, supporting the immune system and a healthy sleep-wake schedule. But they can also be culprits of frustrating body issues, like excess weight that won’t come off ...

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