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A 2018 pooled analysis from three phase III, randomized, double-blind, placebo-controlled studies on usage for Opioid-Induced Constipation, found that the numbers of patients reporting adverse effects were similar in both the lubiprostone and placebo treatment groups for all opioid classes (P ≥ 0.125); however, gastrointestinal adverse ...
Macrogol 4000, pharmaceutical quality. Macrogol 3350, often in combination with electrolytes, is used for short-term relief of constipation as well as for long-term use in constipation of various causes, including in multiple sclerosis and Parkinson's disease patients (an often-overlooked non-motor symptom) as well as constipation caused by pharmaceutical drugs such as opioids and ...
Prucalopride has been given orally to ~2700 patients with chronic constipation in controlled clinical trials. The most frequently reported side effects are headache and gastrointestinal symptoms (abdominal pain, nausea or diarrhea). Such reactions occur predominantly at the start of therapy and usually disappear within a few days with continued ...
The main use is for treatment of constipation. In surgery it is used for pre-operative evacuation of the bowel. [3] In diagnostic testing it is used before x-ray examinations or physical examinations of the colon. It is safe for use in children. [4] If used in children under 3 years, it is recommended that the nozzle is only inserted half way. [5]
Functional constipation: This typically happens when kids hold back bowel movements or after they have a gastrointestinal infection. Many children with constipation have functional constipation ...
Lactulose may be used to counter the constipating effects of opioids, and in the symptomatic treatment of hemorrhoids as a stool softener. [ medical citation needed ] Lactulose is commonly prescribed for children who develop fear of their bowel movements and are withholders.
With nearly half of Americans saying weight loss is a goal for them, it’s no wonder that interest in GLP-1 medications has been on the rise. GLP-1 (short for glucagon-like peptide-1) medications ...
Linaclotide is indicated to treat irritable bowel syndrome with constipation and chronic constipation with no known cause. [ 4 ] [ 3 ] In June 2023, the indication was expanded in the US to include the treatment of functional constipation .
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