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Hippuric acid has long been used as an indicator of toluene exposure; [14] however, there appears to be some doubt about its validity. [15] There is significant endogenous hippuric acid production by humans; which shows inter- and intra-individual variation influenced by factors such as diet, medical treatment, alcohol consumption, etc. [15] This suggests that hippuric acid may be an ...
BPA has major effects on the behavior of vertebrates, especially in their sensory processing systems. In zebrafish BPA can disrupt the signaling in the endocrine system and affect auditory development and function. [111] Similar to a human ear, the zebrafish have a sensory organ called the lateral line that detects different forms of vibration ...
Much of what is known about human lead toxicity and its effects is derived from animal studies. [39] Animals are used to test the effects of treatments, such as chelating agents, [309] and to provide information on the pathophysiology of lead, such as how it is absorbed and distributed in the body. [310]
Health effects of pesticides may be acute or delayed in those who are exposed. [1] Acute effects can include pesticide poisoning, which may be a medical emergency. [2] Strong evidence exists for other, long-term negative health outcomes from pesticide exposure including birth defects, fetal death, [3] neurodevelopmental disorder, [4] cancer, and neurologic illness including Parkinson's disease ...
Metal toxicity or metal poisoning is the toxic effect of certain metals in certain forms and doses on life.Some metals are toxic when they form poisonous soluble compounds. . Certain metals have no biological role, i.e. are not essential minerals, or are toxic when in a certain for
Bioaccumulation is the gradual accumulation of substances, such as pesticides or other chemicals, in an organism. [1] Bioaccumulation occurs when an organism absorbs a substance faster than it can be lost or eliminated by catabolism and excretion.
A biological hazard, or biohazard, is a biological substance that poses a threat (or is a hazard) to the health of living organisms, primarily humans. This could include a sample of a microorganism, virus or toxin that can adversely affect human health. A biohazard could also be a substance harmful to other living beings. [a]
Benign: present in some organisms, sometimes bioaccumulating, but generally having no apparent effects (except possible harmful effects, notes "a" or "b"). 1 Extremely rare on the Earth's surface (less than 1×10 −7 %, i.e. less than 1/10 as common as the least common essential element, selenium), thus has low potential for any kind of ...