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The timing hypothesis, gap hypothesis, gap theory, or critical window hypothesis for menopausal hormone therapy is a scientific theory that the benefits and risks of menopausal hormone therapy vary depending on the amount of time a woman has been in menopause upon initiation of treatment.
Several other reports, including one in 2018 with long-term safety data, reaffirmed hormone therapy’s safety for women who start it before a certain age (basically, it should begin before 60).
Back in 2003, preliminary results were published from the Women’s Health Initiative clinical trial that linked hormone replacement therapy used to treat symptoms of menopause to a higher risk of ...
New studies suggest that hormone therapy for menopause-related symptoms could have a beneficial effect on ... This research team conducted a review and meta-analyses of 17 randomized controlled ...
Hormone replacement therapy (HRT), also known as menopausal hormone therapy or postmenopausal hormone therapy, is a form of hormone therapy used to treat symptoms associated with female menopause. [ 1 ] [ 2 ] Effects of menopause can include symptoms such as hot flashes , accelerated skin aging, vaginal dryness , decreased muscle mass , and ...
Women's Estrogen Lipid-Lowering Hormone Atherosclerosis Regression Trial (WELL-HART) Women's Health Initiative Estrogen Study (WHI-E) Women's Health Initiative Estrogen + Progestin Study (WHI-EP) Women's Health, Osteoporosis, Progestin, Estrogen (Women's HOPE) Women's International Study of Long-Duration Oestrogen After Menopause (WISDOM)
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