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Gas chromatography (GC) is a common type of chromatography used in analytical chemistry for separating and analyzing compounds that can be vaporized without decomposition. Typical uses of GC include testing the purity of a particular substance, or separating the different components of a mixture. [ 1 ]
OpenChrom is an open source software for the analysis and visualization of mass spectrometric and chromatographic data. [4] Its focus is to handle native data files from several mass spectrometry systems (e.g. GC/MS, LC/MS, Py-GC/MS, HPLC-MS), vendors like Agilent Technologies, Varian, Shimadzu, Thermo Fisher, PerkinElmer and others.
Many gas chromatograph detectors are ion detectors with varying methods of ionizing the components eluting from the gas chromatograph's column. [1] [2] An ion detector is analogous to a capacitor or vacuum tube. It can be envisioned as two metal grids separated by air with inverse charges placed on them.
A DID is an ion detector which uses a high-voltage electric discharge to produce ions.The detector uses an electrical discharge in helium to generate high energy UV photons and metastable helium which ionizes all compounds except helium. [1]
Comprehensive two-dimensional gas chromatography, or GC×GC, is a multidimensional gas chromatography technique that was originally described in 1984 by J. Calvin Giddings [1] and first successfully implemented in 1991 by John Phillips and his student Zaiyou Liu. [2] GC×GC utilizes two different columns with two different stationary phases. In ...
Chiral chromatographic assay is the first step in any study pertaining to enantioselective synthesis or separation. This includes the use of techniques viz. gas chromatography (GC), high performance liquid chromatography (HPLC), chiral supercritical fluid chromatography (SFC), capillary electrophoresis (CE) [35] and thin-layer chromatography (TLC).
The thermal conductivity detector (TCD), also known as a katharometer, is a bulk property detector and a chemical specific detector commonly used in gas chromatography. [1] This detector senses changes in the thermal conductivity of the column eluent and compares it to a reference flow of carrier gas. Since most compounds have a thermal ...
Chemical ionization can also be used to identify and quantify an analyte present in a sample, by coupling chromatographic separation techniques to CI [3] such as gas chromatography (GC), high performance liquid chromatography (HPLC) and capillary electrophoresis (CE). This allows selective ionization of an analyte from a mixture of compounds ...