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Elderly patients, 70 years of age and older, receiving intensive chemotherapy have an extremely poor outcome with reported median overall survival (OS) of approximately 4 months in ALL and 6-12 months in AML.
The overall 5-year relative survival rate for AML is 29.8%. However, the outlook for each person will depend on their age, health, the specific genetic mutations present in the leukemia cells,...
Acute myeloid leukemia (AML) survival rates vary on many factors, including age. The overall 5-year survival rate for AML is 29.5% but may be as low as 15% in people over 60.
Our primary aim was to build and assess the validity of a European scoring system for long-term overall survival in AML patients ≥70 years old (ESS70+) who were selected routinely for IC using...
The survival of AML is highly correlated with age. While patients under 40 have 3-year and 5-year survival of 55.8% and 55.1%, respectively, those that are 60–69 or 70–79 have markedly diminished survival of 20.5% and 15.9% and 9.2% and 4.7%, respectively [7]. The 8% 5-year survival noted in the 1970’s has improved to 18% by the 2020’s ...
For example, 5-year survival is over 50% for patients aged 15–24 years that drops steadily to 13% for patients between 60 and 69 years of age and 3% for those aged 70–79 years [ 3 ]. Functional status varies widely even in older patients with similar biological age and affects outcome.
Only 1 in 5 older adults with AML will survive after 1 year, and there is less than 4% chance of 3-year survival. For adults aged 65 to 74 years, the prognosis is only slightly superior. “Thus, on average, being diagnosed with AML at age 65 years or older in the United Stated means dying a decade too soon,” the guideline authors wrote.