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Updates and replaces the 2011 Evaluation, Treatment, and Prevention of Vitamin D Deficiency guideline and focuses on the use of vitamin D to lower the risk of disease in individuals without established indications for vitamin D treatment or 25 (OH)D testing.
Using a cutoff of ≤ 20 ng/ml, an analysis of Na7onal Health and Nutri7on Examina7on Survey (NHANES) data from 2005-2006 found that the overall prevalence rate of vitamin D deficiency among U.S. adults was 41.6%. Rates are significantly higher in blacks and Hispanics compared with whites.
Abstract. Nowadays, in modern societies, many people can be at high risk to have low vitamin D levels. Therefore, testing of serum 25-hydroxy-vitamin D (25OH-D) levels should be performed before prescribing them vitamin D supplementation.
This topic will review the definition, clinical manifestations, and treatment of vitamin D deficiency in adults. The causes of vitamin D deficiency, vitamin D supplementation in osteoporosis, and the treatment of vitamin D deficiency in children are reviewed separately.
A circulating level of 25-hydroxyvitamin D greater than 30 ng/mL is required to maintain a healthy level of vitamin D. Vitamin D deficiency can lead to an array of problems, most notably rickets in children and osteoporosis in adults.
On completion of this article, you should be able to (1) recognize patients at risk for vitamin D deficiency, (2) optimally use and interpret serum vitamin D testing, and (3) determine the optimal vitamin D therapy required to treat or prevent vitamin D deficiency in adults.
The goal of this Review is to compare the 2024 and 2011 Endocrine Society’s Clinical Guidelines on Vitamin D. The 2024 Guideline made recommendations for the general healthy population for skeletal and extra skeletal health benefits of vitamin D. This contrasts with the 2011 Guidelines which provided clinicians with guidance for how to evaluate and treat patients with vitamin D deficiency ...