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  2. Grapefruit can interfere with your medications — here's what ...

    www.aol.com/lifestyle/grapefruit-interfere...

    However, just a single glass of grapefruit juice can block this enzyme and interfere with your body's process of breaking down the medication. "This causes medication levels to remain higher and ...

  3. Grapefruit–drug interactions - Wikipedia

    en.wikipedia.org/wiki/Grapefruitdrug_interactions

    [19] [31] For drugs recently sold on the market, drugs have information pages (monographs) that provide information on any potential interaction between a medication and grapefruit juice. [19] Because there is a growing number of medications that are known to interact with citrus, [ 1 ] patients should consult a pharmacist or physician before ...

  4. Cialis Side Effects: What to Expect (& How to Avoid Them) - AOL

    www.aol.com/cialis-side-effects-expect-avoid...

    Interaction With Antifungal Medications. Cialis can interact with some oral antifungal medications, like itraconazole or ketoconazole, used to treat ringworm, dandruff, or fungal nail infections ...

  5. Drug interaction - Wikipedia

    en.wikipedia.org/wiki/Drug_interaction

    When two drugs affect each other, it is a drugdrug interaction (DDI). The risk of a DDI increases with the number of drugs used. [1] A large share of elderly people regularly use five or more medications or supplements, with a significant risk of side-effects from drugdrug interactions. [2] Drug interactions can be of three kinds:

  6. Grapefruit juice - Wikipedia

    en.wikipedia.org/wiki/Grapefruit_juice

    Grapefruit and grapefruit juice have been found to interact with numerous drugs, in many cases resulting in adverse effects. [4] This happens in two ways: one is that grapefruit can block an enzyme which metabolizes medication, [5] and if the drug is not metabolized, then the level of the drug in the blood can become too high, leading to an adverse effect. [5]

  7. CYP3A4 - Wikipedia

    en.wikipedia.org/wiki/CYP3A4

    The effect of grapefruit juice with regard to drug absorption was originally discovered in 1989. The first published report on grapefruit drug interactions was in 1991 in the Lancet entitled "Interactions of Citrus Juices with Felodipine and Nifedipine", and was the first reported food-drug interaction clinically. The effects of grapefruit last ...

  8. Grapefruit can interfere with your medications — here's what ...

    www.aol.com/grapefruit-interfere-medications...

    A single glass of grapefruit juice can interfere with your body's ability to break down a medication. Here's how to protect your health.

  9. Can I Have Grapefruit with Cialis? - AOL

    www.aol.com/grapefruit-cialis-115700221.html

    In the case of grapefruit and Cialis, this liquid or the fruit itself produces an unwanted effect — known as a “drug interaction.” Cialis also interacts with drugs like alpha blockers and ...