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USP 800 (Hazardous Drugs—Handling in Healthcare Settings) is a guideline created by the United States Pharmacopeia Convention (USP), as one of their General Chapters through which the USP "sets quality standards for medicines, dietary supplements and food ingredients".
Genotoxicity might involve carcinogenicity, the ability to cause cancer in animal models, humans or both; teratogenicity, which is the ability to cause defects on fetal development or fetal malformation; and lastly hazardous drugs are known to have the potential to cause fertility impairment, which is a major concern for most clinicians. [1]
"A drug transfer device that mechanically prohibits the transfer of environmental contaminants into the system and the escape of the hazardous drug or vapor concentrations outside the system". [ 8 ] CSTDs generally follow one of two design concepts, using either a physical barrier or an air-cleaning technology to prevent the escape of hazardous ...
NIOSH was created by the Occupational Safety and Health Act of 1970 [27] and began operating in May 1971. [25] It was originally part of the Health Services and Mental Health Administration, and was transferred into what was then called the Center for Disease Control (CDC) in 1973. [27] NIOSH's initial headquarters were located in Rockville ...
The NIOSH occupational exposure banding process has been created to provide a reliable approximation of a safe exposure level for potentially hazardous and unregulated chemicals in the workplace. [6] Occupational exposure banding uses limited chemical toxicity data to group chemicals into one of five bands. Occupational exposure bands: [7]
An occupational exposure limit is an upper limit on the acceptable concentration of a hazardous substance in workplace air for a particular material or class of materials. It is typically set by competent national authorities and enforced by legislation to protect occupational safety and health.
National Institute for Occupational Safety and Health (NIOSH) RELs are designed to protect the health and well-being of workers by recommending safe exposure levels. To really use these guidelines well, safety professionals need to understand the recommended exposure levels, how to measure them, and ways to make sure workers aren't exposed to harmful stuff.
Exposure monitoring analyzes hazardous substances in the air or on surfaces of a workplace, and is complementary to biomonitoring, which instead analyzes toxicants or their effects within workers. A wide array of methods and instrumentation are used in workplace exposure monitoring.