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Fel d 1 is the most prominent cat allergen, accounting for 96% of human cat allergies. [4] The remaining cat allergens are Fel d 2–8, [5] with Fel d 4, a major urinary protein found in the saliva of cats, [6] occurring the most in humans among the other seven allergens. All cats produce Fel d 1, including hypoallergenic cats.
Allergy testing can help confirm or rule out allergies and consequently reduce adverse reactions and limit unnecessary avoidance and medications. [1] [2]Correct allergy diagnosis, counseling and avoidance advice based on valid allergy test results is of utmost importance and can help reduce the incidence of symptoms, and the need for medications and improve quality of life. [2]
Food allergies account for approximately 10% of allergies in both dogs and cats. [5] Food allergies are often mistaken for food intolerances, which can result in vomiting and diarrhea instead of dermal issues. In most cases where food allergies occur, they do so with foods that cats eat most often. Common food allergens in cats include beef ...
Fel d 1 is a secretoglobin protein complex that, in cats, is encoded by the CH1 (chain 1/Fel d 1-A) and CH2 (chain 2/Fel d 1-B) genes. [2] [3] Among cats, Fel d 1 is produced largely in their saliva and by the sebaceous glands located in their skin. It is the primary allergen present on cats and kittens.
Adults and children of any age can get an allergy blood test. For babies and very young children, a single needle stick for allergy blood testing is often gentler than several skin pricks. An allergy blood test is available through most laboratories. A sample of the patient's blood is sent to a laboratory for analysis, and the results are sent ...
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The RAST is a radioimmunoassay test to detect specific IgE antibodies to suspected or known allergens for the purpose of guiding a diagnosis about allergy. [10] [11] IgE is the antibody associated with Type I allergic response: for example, if a person exhibits a high level of IgE directed against pollen, the test may indicate the person is allergic to pollen (or pollen-like) proteins.