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Laboratory tests such as measuring the peak serum iron level after 4 to 6 hours of ingestion can be useful in determining the severity of iron toxicity. [4] In general, levels below 350mcg/dL are associated with more mild iron poisoning while upper levels above 500mcg/dL are associated with more severe iron poisoning. [3]
Iron overload (also known as haemochromatosis or hemochromatosis) is the abnormal and increased accumulation of total iron in the body, leading to organ damage. [1] The primary mechanism of organ damage is oxidative stress, as elevated intracellular iron levels increase free radical formation via the Fenton reaction.
Metal toxicity or metal poisoning is the toxic effect of certain metals in certain forms and doses on life. Some metals are toxic when they form poisonous soluble compounds. Certain metals have no biological role, i.e. are not essential minerals, or are toxic when in a certain form. [ 1 ]
966 Poisoning by anticonvulsants and anti-Parkinsonism drugs; 967 Poisoning by sedatives and hypnotics; 968 Poisoning by other Central nervous system depressants and anesthetics; 969 Poisoning by psychotropic agents. 969.0 Poisoning by antidepressants; 969.1 Poisoning by phenothiazine-based tranquilizers; 969.2 Poisoning by butyrophenone-based ...
An antidote is a substance that can counteract a form of poisoning. [1] The term ultimately derives from the Greek term φάρμακον ἀντίδοτον (pharmakon antidoton) , "(medicine) given as a remedy".
The death toll from fentanyl is falling as communities flood the streets with naloxone, an overdose-reversal drug. But deadly opioids remain rife. A fentanyl antidote is saving lives.
Iron toxicity results when the amount of circulating iron exceeds the amount of transferrin available to bind it, but the body is able to vigorously regulate its iron uptake. Thus, iron toxicity from ingestion is usually the result of extraordinary circumstances like iron tablet over-consumption [1] [ 42 ] rather than variations in diet .
After years of continuously rising opioid overdoses, the US Centers for Disease Control and Prevention reported that overdose deaths decreased 3% in 2023, the first annual decrease since 2018. A ...