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  2. Dissociative - Wikipedia

    en.wikipedia.org/wiki/Dissociative

    [4] [5] [6] According to Pender (1972), "the state has been designated as dissociative anesthesia since the patient truly seems disassociated from his environment." [ 7 ] Both Pender (1970) and Johnstone et al. (1959) reported that patients under anaesthesia due to either ketamine or phencyclidine were prone to purposeless movements and had ...

  3. NMDA receptor antagonist - Wikipedia

    en.wikipedia.org/wiki/NMDA_receptor_antagonist

    NMDA receptor antagonists induce a state called dissociative anesthesia, marked by catalepsy, amnesia, and analgesia. [1] Ketamine is a favored anesthetic for emergency patients with unknown medical history and in the treatment of burn victims because it depresses breathing and circulation less than other anesthetics.

  4. Ketamine - Wikipedia

    en.wikipedia.org/wiki/Ketamine

    At anesthetic doses, ketamine induces a state of dissociative anesthesia, a trance-like state providing pain relief, sedation, and amnesia. [21] Its distinguishing features as an anesthestic are preserved breathing and airway reflexes, stimulated heart function with increased blood pressure , and moderate bronchodilation . [ 21 ]

  5. Category:Dissociative drugs - Wikipedia

    en.wikipedia.org/wiki/Category:Dissociative_drugs

    Print/export Download as PDF; Printable version; ... Pages in category "Dissociative drugs" The following 93 pages are in this category, out of 93 total.

  6. Tiletamine - Wikipedia

    en.wikipedia.org/wiki/Tiletamine

    Tiletamine is a dissociative anesthetic and pharmacologically classified as an NMDA receptor antagonist. [1] It is related chemically to ketamine . [ 2 ] Tiletamine hydrochloride exists as odorless white crystals.

  7. Procedural sedation and analgesia - Wikipedia

    en.wikipedia.org/wiki/Procedural_sedation_and...

    Procedural sedation and analgesia (PSA) is a technique in which a sedating/dissociative medication is given, usually along with an analgesic medication, in order to perform non-surgical procedures on a patient. The overall goal is to induce a decreased level of consciousness while maintaining the patient's ability to breathe on their own.

  8. SN 35210 - Wikipedia

    en.wikipedia.org/wiki/SN_35210

    SN 35210 is an arylcyclohexylamine dissociative anesthetic drug. It was derived from ketamine with the intention of producing a shorter acting agent more suitable to be used as a stand-alone drug, whereas ketamine itself generally has to be used in combination with other drugs such as midazolam to minimise the occurrence of emergence reactions due to its hallucinogenic side effects.

  9. Olney's lesions - Wikipedia

    en.wikipedia.org/wiki/Olney's_lesions

    Olney's lesions, also known as NMDA receptor antagonist neurotoxicity (NAT), is a form of brain damage consisting of selective death of neurons but not glia, observed in restricted brain regions of rats and certain other animal models exposed to large quantities of psychoactive drugs that inhibit the normal operation of the neuronal NMDA receptor.