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  2. Conditions comorbid to autism - Wikipedia

    en.wikipedia.org/wiki/Conditions_comorbid_to_autism

    Unusual responses to sensory stimuli are more common and prominent in individuals with autism, and sensory abnormalities are commonly recognized as diagnostic criteria in autism spectrum disorder (ASD), as reported in the DSM-5; although there is no good evidence that sensory symptoms differentiate autism from other developmental disorders. [84]

  3. Acetylserotonin O-methyltransferase - Wikipedia

    en.wikipedia.org/wiki/Acetylserotonin_O-methyl...

    HIOMT as the limiting reagent in the melatonin biosynthetic pathway There has been some controversy over the regulatory power of hydroxyindole-O-methyltransferase in the production of melatonin. In 2001, it was argued that another enzyme in the pathway, N-acetyl transferase (NAT) was the limiting reagent in the production of melatonin. [ 18 ]

  4. Autism - Wikipedia

    en.wikipedia.org/wiki/Autism

    Autism spectrum disorder [a] (ASD), or simply autism, is a neurodevelopmental disorder "characterized by persistent deficits in social communication and social interaction across multiple contexts" and "restricted, repetitive patterns of behavior, interests, or activities". [11] Sensory abnormalities are also included in the diagnostic manuals ...

  5. Melatonin as a medication and supplement - Wikipedia

    en.wikipedia.org/wiki/Melatonin_as_a_medication...

    Melatonin may be useful in the treatment of delayed sleep phase syndrome. [9] Melatonin is known to reduce jet lag, especially in eastward travel. However, if it is not taken at the correct time, it can instead delay adaptation. [30] Melatonin appears to have limited use against the sleep problems of people who work shift work. [31]

  6. Mechanism of autism - Wikipedia

    en.wikipedia.org/wiki/Mechanism_of_autism

    A 2012 meta-analysis study, as well as other population studies show that approximately 5% of autistic children meet the criteria for classical mitochondrial dysfunction. [63] It is unclear why this mitochondrial disease occurs, considering that only 23% of children with both ASD and mitochondrial disease present with mitochondrial DNA ...

  7. Autism therapies - Wikipedia

    en.wikipedia.org/wiki/Autism_therapies

    It is now known that "children with ASD are at risk of having alimentary tract disorders – mainly, they are at a greater risk of general gastrointestinal (GI) concerns, constipation, diarrhea, and abdominal pain" [194] [195] [196] and as succinctly summarized the Mayo Clinic website in 2019, "Yes, children with autism spectrum disorder (ASD ...

  8. Outline of autism - Wikipedia

    en.wikipedia.org/wiki/Outline_of_autism

    Relationship Development Intervention (RDI) – a trademarked proprietary treatment program for autism spectrum disorders (ASD), based on the belief that the development of dynamic intelligence is the key to improving the quality of life for individuals with autism. Son-Rise – a therapy encouraging adults to connect with autistic children.

  9. Melatonin receptor agonist - Wikipedia

    en.wikipedia.org/wiki/Melatonin_receptor_agonist

    The melatonin receptors consist of proteins around 40 kDa each. The MT 1 receptor encodes 350 amino acids and the MT 2 encodes 362 amino acids. The binding of melatonin and its analogues is now understood through X-ray crystal structures published in 2019. [17] The binding space for melatonin and analogues on the MT 1 receptor is smaller than ...

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