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Paired samples t-tests typically consist of a sample of matched pairs of similar units, or one group of units that has been tested twice (a "repeated measures" t-test). A typical example of the repeated measures t-test would be where subjects are tested prior to a treatment, say for high blood pressure, and the same subjects are tested again ...
A paired difference test, better known as a paired comparison, is a type of location test that is used when comparing two sets of paired measurements to assess whether their population means differ. A paired difference test is designed for situations where there is dependence between pairs of measurements (in which case a test designed for ...
Statistical tests are used to test the fit between a hypothesis and the data. [1] [2] Choosing the right statistical test is not a trivial task. [1]The choice of the test depends on many properties of the research question.
In statistics, particularly in hypothesis testing, the Hotelling's T-squared distribution (T 2), proposed by Harold Hotelling, [1] is a multivariate probability distribution that is tightly related to the F-distribution and is most notable for arising as the distribution of a set of sample statistics that are natural generalizations of the statistics underlying the Student's t-distribution.
For two matched samples, it is a paired difference test like the paired Student's t-test (also known as the "t-test for matched pairs" or "t-test for dependent samples"). The Wilcoxon test is a good alternative to the t-test when the normal distribution of the differences between paired individuals cannot be assumed. Instead, it assumes a ...
A very simple equivalence testing approach is the ‘two one-sided t-tests’ (TOST) procedure. [11] In the TOST procedure an upper (Δ U) and lower (–Δ L) equivalence bound is specified based on the smallest effect size of interest (e.g., a positive or negative difference of d = 0.3).
The Newman–Keuls method employs a stepwise approach when comparing sample means. [15] Prior to any mean comparison, all sample means are rank-ordered in ascending or descending order, thereby producing an ordered range (p) of sample means. [1] [15] A comparison is then made between the largest and smallest sample means within the largest ...
To test whether allele a is recessive to allele A, the optimal choice is t = (0, 1, 1). To test whether alleles a and A are codominant, the choice t = (0, 1, 2) is locally optimal. For complex diseases, the underlying genetic model is often unknown. In genome-wide association studies, the additive (or codominant) version of the test is often ...