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Hence, 4-AcO-DMT results in modestly lower psilocin levels than psilocybin even when the drugs are given at equivalent doses with adjustment for differences in molecular weight. [2] Along similar lines, the psilocin concentrations with 4-AcO-DMT 15 minutes after administration were 75 to 90% of those of an equimolar dose of psilocybin. [2]
[1] [3] [4] [5] There have also been earlier instances of such stores, for example in Europe in the 2000s. [6] [7] In addition, magic mushroom products are or have been sold by stores and cafes in other parts of the world. [8] [9] [10] The stores may sell actual hallucinogenic mushrooms such as psilocybin mushrooms and Amanita muscaria mushrooms.
Psilacetin (O-acetylpsilocin; 4-AcO-DMT) – non-selective serotonin receptor agonist and psychedelic hallucinogen – substance-related disorders – Psilera [180] Psilocin (PLZ-1015) – non-selective serotonin receptor agonist and psychedelic hallucinogen – pervasive child development disorders – Pilz Bioscience [ 181 ]
In rodents, 4-HO-TMT showed no head-twitch response (a behavioral proxy of psychedelic effects), hypolocomotion, or hypothermia, in contrast to psilocin and norpsilocin, but similarly to aeruginascin. [3] A synthetic prodrug of 4-HO-TMT, 4-AcO-TMT, has been developed. [1] [5] It is analogous to psilacetin (4-AcO-DMT), a prodrug of psilocin. [1] [5]
Psilocin (4-HO-DMT) is the dephosphorylated active metabolite of the indole alkaloid psilocybin and a substituted tryptamine, which is produced in over 200 species of fungi. Of the classical psychedelics psilocybin has attracted the greatest academic interest regarding its ability to manifest mystical experiences, [ 50 ] although all ...
An assortment of several designer drugs. Designer drugs are structural or functional analogues of controlled substances that are designed to mimic the pharmacological effects of the parent drug while avoiding detection or classification as illegal.
O-Acetylbufotenine, or bufotenine O-acetate, also known as 5-acetoxy-N,N-dimethyltryptamine (5-AcO-DMT) or O-acetyl-N,N-dimethylserotonin, is a synthetic tryptamine derivative and putative serotonergic psychedelic.
4-acetoxy-MET (4-acetoxy-N-methyl-N-ethyl tryptamine), also known as 4-AcO-MET or metacetin, is a hallucinogenic tryptamine. It is the acetate ester of 4-HO-MET, and a homologue of 4-AcO-DMT. It is a novel compound with very little history of human use. [2] It is sometimes sold as a research chemical by online retailers.