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In modern times, depression, more often severe cases, is more noted as an absence of pleasure, with feelings of emptiness and flatness. [4] In the United States and Canada, the costs associated with major depression are comparable to those related to heart disease, diabetes, and back problems and are greater than the costs of hypertension. [5]
Late-life depression is often underdiagnosed, which is due to numerous reasons, including that depressed mood is commonly not as prominent as other somatic and psychotic symptoms such as loss of appetite, disruptions in sleep, lack of energy or anergia, fatigue, and loss of interest and enjoyment in normal life activities.
Sleep hygiene is important—but there’s one key factor impacting insomnia the most that experts want you to focus on. Insomnia affects up to 50% of adults and can hurt your body and brain ...
If PKA or protein synthesis inhibition occurs at certain moments during sleep, memory consolidation can be disrupted [citation needed]. In addition, mice with genetic inhibition of PKA have been shown to have long-term memory deficits. [48] Thus, sleep deprivation may act through the inhibition of these protein synthesis pathways.
Some sleep specialists recommend biofeedback as well. [2] Usually, several methods are combined into an overall treatment plan. [3] Currently no treatment method is recommended over another. [4] CBT-I has been found to be an effective form of treatment of traditional insomnia, as well as insomnia related to or caused by mood disorders or PTSD.
Sleep debt or sleep deficit is the cumulative effect of not getting enough sleep. A large sleep debt may lead to mental or physical fatigue, and can adversely affect one's mood, energy, and ability to think clearly. There are two kinds of sleep debt: the result of partial sleep deprivation, and of total sleep deprivation
One factor that could explain this change in sleep architecture is a disruption in the circadian rhythm, which regulates sleep. [19] This disruption can lead to sleep disturbances. [19] Some studies show that people with Alzheimer's disease have a delayed circadian rhythm, whereas in normal aging, an advanced circadian rhythm is present. [19] [20]
Depression is sometimes associated with insomnia (difficulty in falling asleep, early waking, or waking in the middle of the night). The combination of these two results, depression and insomnia, will only worsen the situation. Hence, good sleep hygiene is important to help break this vicious circle. [183]
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