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Liver damage, [3] nausea, vomiting, epigastric and abdominal pain, diarrhoea, anxiety, headache and convulsions, often followed by coma [10] Ayurvedic Herbo-mineral (Rasashastra) Medicines Heavy metal contamination [11] Bitter orange 'Fainting, arrhythmia, heart attack, stroke, death' [4] Broom
Phytate. A phytase (myo-inositol hexakisphosphate phosphohydrolase) is any type of phosphatase enzyme that catalyzes the hydrolysis of phytic acid (myo-inositol hexakisphosphate) – an indigestible, organic form of phosphorus that is found in many plant tissues, especially in grains and oil seeds – and releases a usable form of inorganic phosphorus. [1]
For example, the anti-obesity drug orlistat causes a percentage of fat to pass through the digestive tract undigested. [9] Amylase inhibitors prevent the action of enzymes that break the glycosidic bonds of starches and other complex carbohydrates, preventing the release of simple sugars and absorption by the body. Like lipase inhibitors, they ...
The hexavalent phytate anion. Phytic acid was discovered in 1903. [2] Generally, phosphorus and inositol in phytate form are not bioavailable to non-ruminant animals because these animals lack the enzyme phytase required to hydrolyze the inositol-phosphate linkages. Ruminants are able to digest phytate because of the phytase produced by rumen ...
About 12.2 million new strokes are diagnosed each year. One in four stroke survivors will experience another stroke. Stroke survivors are at an increased risk of developing major heart issues ...
inositol hexaphosphate (IP 6) also known as phytic acid, or phytate (as a salt). A series of phosphorylation and dephosphorylation reactions are carried out by at least 19 phosphoinositide kinases and 28 phosphoinositide phosphatase enzymes [ 1 ] allowing for the inter-conversion between the inositol phosphate compounds based on cellular demand.
High Ca 2+ concentration can enhance BPP catalysis rate up to a limit. When Ca 2+ concentration surpasses this limit, extra Ca 2+ ions begin to work as competitive inhibitors. High concentrations of free phytate which not bound to Ca 2+ also inhibits BPPs. This happens possibly via free phytate mediated chelation of the Ca 2+ bound to BPPs. [4]
Brain ischemia has been linked to a variety of diseases or abnormalities. Individuals with sickle cell anemia, compressed blood vessels, ventricular tachycardia, plaque buildup in the arteries, blood clots, extremely low blood pressure as a result of heart attack, and congenital heart defects have a higher predisposition to brain ischemia in comparison to the average population.