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Methamphetamine [note 1] (contracted from N-methylamphetamine) is a potent central nervous system (CNS) stimulant that is mainly used as a recreational or performance-enhancing drug and less commonly as a second-line treatment for attention deficit hyperactivity disorder (ADHD). [24]
The use of stimulant medication for treatment of attention-deficit hyperactivity disorder (ADHD) is well-researched and considered one of the most effective treatments in psychiatry. [89] A 2015 study examined the long-term effects of stimulant medication for ADHD, and reported that stimulants are a highly effective treatment for ADHD in the ...
Amphetamine is currently indicated in the United States for ADHD and narcolepsy, with lisdexamfetamine (a prodrug) indicated for binge eating disorder; [12] [13] and methamphetamine is indicated for ADHD, [14] though prescribed at significantly lower rates compared to amphetamine. [15]
In 2021, about 1.6 million people ages 12 and up in the U.S. had a methamphetamine use disorder and 1.4 million had a cocaine use disorder, according to data from the Substance Abuse and Mental ...
Symptoms overlapping with ADHD in psychotic disorders may be limited to psychotic states. Substance use disorder, some medications, and certain medical conditions may cause symptoms to appear later in life, while ADHD, as a neurodevelopmental disorder, requires for them to have been present since childhood.
Methamphetamine (contracted from N-methyl-alpha-methylphenethylamine) is a potent psychostimulant of the phenethylamine and amphetamine classes that is used to treat attention deficit hyperactivity disorder (ADHD) and obesity. [139] [140] [141] Methamphetamine exists as two enantiomers, dextrorotary and levorotary.
ATS use disorders are related to the GABA system. Research shows that ATS use would affect normal function of the GABAA receptors. [9] Clonazepam, which is a GABAA receptor agonist, is shown to prevent the acquisition of behavioural sensitization to methamphetamine. GABAA receptor antagonist is shown to aggravate ATS use disorders.
[3] [4] [5] Methamphetamine psychosis, or long-term effects of stimulant use in the brain (at the molecular level), depend upon genetics and may persist for months or years. [6] Psychosis may also result from withdrawal from stimulants, particularly when psychotic symptoms were present during use. [7]