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In vertebrates, the olfactory receptors are located in both the cilia and synapses of the olfactory sensory neurons [5] and in the epithelium of the human airway. [6] Sperm cells also express odor receptors, which are thought to be involved in chemotaxis to find the egg cell.
Humans have between 10 and 20 million olfactory receptor neurons (ORNs). [3] In vertebrates, ORNs are bipolar neurons with dendrites facing the external surface of the cribriform plate with axons that pass through the cribriform foramina with terminal end at olfactory bulbs. The ORNs are located in the olfactory epithelium in the
Humans have far fewer active odor receptor genes than other primates and other mammals. [11] In mammals, each olfactory receptor neuron expresses only one functional odor receptor. [12] Odor receptor nerve cells function like a key–lock system: if the airborne molecules of a certain chemical can fit into the lock, the nerve cell will respond.
8590 18317 Ensembl ENSG00000184933 ENSMUSG00000070417 UniProt O95222 n/a RefSeq (mRNA) NM_003696 NM_010983 RefSeq (protein) NP_003687 n/a Location (UCSC) Chr 11: 6.79 – 6.8 Mb Chr 7: 106.59 – 106.61 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Olfactory receptor 6A2 is a protein that in humans is encoded by the OR6A2 gene. It is Class II (tetrapod -specific) olfactory receptor ...
The olfactory system, is the sensory system used for the sense of smell (olfaction). Olfaction is one of the special senses directly associated with specific organs. Most mammals and reptiles have a main olfactory system and an accessory olfactory system.
Located in the temporal lobe, the primary olfactory cortex is the primary receptive area for olfaction, or smell. Unique to the olfactory and gustatory systems, at least in mammals , is the implementation of both peripheral and central mechanisms of action.
The olfactory nerve zone is composed of preterminals and terminals of the olfactory nerve and is where the olfactory receptor cells make synapses on their targets. [2] The non-olfactory nerve zone is composed of the dendritic processes of intrinsic neurons and is where dendrodendritic interactions between intrinsic neurons occur. [2]
The human leukocyte antigen system is a protein complex which is encoded by MHC in humans. Over thirty olfactory receptor genes have been located at the HLA class I region, [36] which presents peptides from inside the cell to be destroyed by the immune system. HLA- linked olfactory receptor genes can therefore provide a possible mechanism for ...