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People suffered from "chronic or recurrent fatigue", among a large number of other symptoms. [1]: 28–29 The initial link between elevated antibodies and the Epstein–Barr virus led to the name "chronic Epstein–Barr virus syndrome". The CDC renamed it chronic fatigue syndrome (CFS), as a viral cause could not be confirmed in studies.
Graded exercise therapy (GET) is a programme of physical activity that starts very slowly and gradually increases over time, intended as a treatment for myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). Most public health bodies, including the CDC and NICE, consider it ineffective, and its safety is disputed.
Management of ME/CFS (myalgic encephalomyelitis/chronic fatigue syndrome) focuses on symptoms management, as no treatments that address the root cause of the illness are available. [1]: 29 Pacing, or regulating one's activities to avoid triggering worse symptoms, is the most common management strategy for post-exertional malaise.
The initial chronic fatigue syndrome definition was published in 1988. It is also called the "Holmes definition", after the manuscript's first author. [10] The Homes criteria require these two points: Debilitating fatigue of new onset which interferes with the patient's daily activities; Other fatiguing conditions must be eliminated
The term “fatigue” trivialises the illness and discourages research into potential treatments. [91] According to a survey of medical trainees at a school in the United States, a condition described as "chronic fatigue syndrome" is considered less serious than a condition described as "myalgic encephalopathy". [92] [93]
It is the hallmark symptom of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and common in long COVID and fibromyalgia. [3] [1] PEM is often severe enough to be disabling, and is triggered by ordinary activities that healthy people tolerate. Typically, it begins 12–48 hours after the activity that triggers it, and lasts for days ...
Post-exertional malaise is a worsening of symptoms after minimal physical or mental activity, [6] and is a cardinal symptom of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). [7] Both PEM and exercise intolerance are common in long COVID. [8] [9] Orthostatic intolerance (OI) occurs in ME/CFS. OI includes exercise intolerance as one ...
Evidence for a positive effect of CBT has been found in trials for fibromyalgia, chronic fatigue syndrome, irritable bowel syndrome, unexplained headaches, unexplained back pain, tinnitus, and non-cardiac chest pain. [25] Overall, CBT has been shown to be effective in reducing psychological distress and improving medical status in MUPS patients.