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The following are medications commonly prescribed cardiac pharmaceutical agents. The specificity of the following medications is highly variable, and often are not particularly specific to a given class. As such, they are listed as are commonly accepted.
Antiarrhythmic agents, also known as cardiac dysrhythmia medications, are a class of drugs that are used to suppress abnormally fast rhythms (tachycardias), such as atrial fibrillation, supraventricular tachycardia and ventricular tachycardia. Many attempts have been made to classify antiarrhythmic agents.
A number of drugs that cause QT prolongation does not directly block hERG, but reduces the trafficking of the mature protein to the surface of the cell. This includes probucol , which appears to enhance the intercellular degradation of hERG; and several cardiac glycosides , which reduces trafficking due to decreased intracellular potassium.
Supraventricular tachycardia (SVT) is an umbrella term for fast heart rhythms arising from the upper part of the heart. [2] This is in contrast to the other group of fast heart rhythms – ventricular tachycardia , which start within the lower chambers of the heart . [ 2 ]
It is a type of supraventricular tachycardia (SVT), meaning that it originates from a location within the heart above the bundle of His. AV nodal reentrant tachycardia is the most common regular supraventricular tachycardia. It is more common in women than men (approximately 75% of cases occur in females). The main symptom is palpitations.
The medications that most commonly cause first-degree heart block are those that increase the refractory time of the AV node, thereby slowing AV conduction. These include calcium channel blockers , beta-blockers , cardiac glycosides , and anything that increases cholinergic activity such as cholinesterase inhibitors .
Postural orthostatic tachycardia syndrome (POTS) is a condition characterized by an abnormally large increase in heart rate upon sitting up or standing. [1] POTS is a disorder of the autonomic nervous system that can lead to a variety of symptoms, [10] including lightheadedness, brain fog, blurred vision, weakness, fatigue, headaches, heart palpitations, exercise intolerance, nausea ...
Other drugs, such as sympatholytics and cholinesterase inhibitors like pyridostigmine, have very limited clinical evidence. There have been no randomized controlled trials regarding the use of these drugs in the treatment of Inappropriate sinus tachycardia, and all, with the possible exception of β-blockers, should be considered off-label ...