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  2. In 2002, a second risk-management program, the System to Manage Accutane-Related Teratogenicity (SMART), was instituted, introducing a requirement of two negative pregnancy tests before starting ...

  3. iPLEDGE program - Wikipedia

    en.wikipedia.org/wiki/IPLEDGE_program

    Once a doctor decides a patient is a candidate for isotretinoin, [10] they counsel the patient to ensure they understand the drug and the potential side effects. Once the patient signs the necessary paperwork, their doctor will give them a patient ID number, ID card, and program educational materials.

  4. List of SJS-inducing substances - Wikipedia

    en.wikipedia.org/wiki/List_of_SJS-inducing...

    Glutathione [9] Ibuprofen [10] Isotretinoin [11] Accutane Lamotrigine [12] Lamictal Modafinil [13] Provigil Nevirapine [citation needed] Norfloxacin [14] Oseltamivir [citation needed] Oxicams [7] Ampiroxicam, Piroxicam, Tenoxicam, Droxicam, Lornoxicam, Meloxicam, Isoxicam: Paracetamol [15] [16] Acetaminophen, Panadol, Tylenol Penicillins [5 ...

  5. Isotretinoin - Wikipedia

    en.wikipedia.org/wiki/Isotretinoin

    Isotretinoin is a teratogen highly likely to cause birth defects if taken by women during pregnancy or even a short time before conception. A few of the more common birth defects this drug can cause are hearing and visual impairment, missing or malformed earlobes, facial dysmorphism, and abnormalities in brain function.

  6. AOL Video - Serving the best video content from AOL and ...

    www.aol.com/video/view/the-dangers-of-using...

    The AOL.com video experience serves up the best video content from AOL and around the web, curating informative and entertaining snackable videos.

  7. Drugs in pregnancy - Wikipedia

    en.wikipedia.org/wiki/Drugs_in_pregnancy

    Gestational diabetes is a form of diabetes that is first diagnosed during pregnancy and can accordingly cause high blood sugar that affects the woman and the baby. [9] In 10 - 20% of women whose diet and exercise are not adequate enough to control blood sugar, insulin injections may be required to lower blood sugar levels. [ 9 ]

  8. Tretinoin - Wikipedia

    en.wikipedia.org/wiki/Tretinoin

    Other severe side effects include high white blood cell counts and blood clots. [8] Use during pregnancy is contraindicated due to the risk of birth defects. [8] [1] It is in the retinoid family of medications. [9] Tretinoin was patented in 1957 and approved for medical use in 1962. [13] It is on the World Health Organization's List of ...

  9. Erythromycin/isotretinoin - Wikipedia

    en.wikipedia.org/wiki/Erythromycin/isotretinoin

    Some of the side effects are related to vitamin A toxicity. [1] Very common (≥ 1/10) Common (≥ 1/100, < 1/10) Unknown frequency Skin pain Dermatitis: