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Needles used in a core biopsy are slightly larger than those used in FNA. They remove a small cylinder (“core”) of tissue. A core needle biopsy (CNB) is most often done using local anesthesia (numbing medicine) in a doctor’s office or clinic.
Core needle biopsy. A larger needle with a cutting tip is used during core needle biopsy to draw a column of tissue out of a suspicious area. Vacuum-assisted biopsy. During vacuum-assisted biopsy, a suction device increases the amount of fluid and cells that is extracted through the needle.
A core needle biopsy is the standard and preferred way to diagnose breast cancer. In rare cases, a surgical breast biopsy may be needed for diagnosis. The tissue removed during a surgical biopsy is studied under a microscope to see if breast cancer is present.
Core needle biopsy of the breast. A larger needle is used in a core needle biopsy. Small pieces of breast tissues, also called “cores,” are removed during this procedure. The care team uses an ultrasound, MRI or mammogram during the biopsy so they can guide the needle precisely where it needs to go.
Most often this will be a core needle biopsy (CNB) or a fine needle aspiration (FNA). But in some situations, such as if the results of a needle biopsy aren’t clear, you might need a surgical biopsy (sometimes called an open biopsy). What is a surgical biopsy?
A core needle biopsy provides more material, and therefore more information, than an FNA—but less material than a surgical biopsy. For breast lesions, a core needle biopsy may be performed quickly, with a low risk of infection or excessive bruising.
Needle biopsy has replaced excisional biopsy as a definitive diagnostic technique for breast tumours, although excisional biopsy is still used for complete tumour removal for therapeutic and/or diagnostic purposes.
Background: When a breast lesion is suspected based on a physical exam, mammography, or ultrasound, a stereotactic core needle biopsy (CNB) is usually performed to help establish a definitive diagnosis. CNBs are far less invasive than excisional biopsies, with no need for general anesthetics or hospitalization, and no recovery period.
An excisional biopsy is a type of biopsy that removes an entire tumor and some of the skin around it. Learn when it's used, what it's like, and more.
Diagnostic procedures. Biopsy. This page was reviewed under our medical and editorial policy by. Maurie Markman, MD, President, Medicine & Science. This page was updated on June 13, 2022. A health care provider may recommend a biopsy if an exam or test reveals something suspicious. This article will cover: What is a biopsy?