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While all PPIs work similarly, some are more effective than others. Researchers compare the potency of AcipHex, Nexium, Prevacid, and Protonix based on milligram (mg) equivalence to Prilosec.
Compare Nexium vs Protonix head-to-head with other drugs for uses, ratings, cost, side effects and interactions.
Pantoprazole (Protonix) isn't available over-the-counter (OTC). Esomeprazole (Nexium) is a medication used to treat conditions that are caused by too much stomach acid, such as heartburn or acid reflux. It's available both with a prescription and over the counter (OTC).
Nexium vs Protonix are both potent acid-suppressing medications known as proton pump inhibitors (PPIs), but a key difference lies in their chemical structure: Nexium is an enantiomer, potentially offering more consistent and rapid acid reduction, while Protonix is valued for its efficacy in managing a variety of acid-related conditions.
Two studies of esomeprazole (Nexium) 40 mg versus omeprazole 20 mg found a small difference. The “cure rate” of 79.6 versus 67.3 percent results in a number needed to treat (NNT) of 8.
Omeprazole (Prilosec) and pantoprazole (Protonix) are oral drugs belonging to the proton pump inhibitors (PPIs) drug class. Omeprazole and pantoprazole treat gastroesophageal reflux disease (GERD) symptoms like heartburn. While similar, they carry notable differences that users should understand.
Written by Juhi Modi. Medically reviewed by HaVy Ngo-Hamilton, Pharm.D. | Updated Aug 15, 2022. Proton pump inhibitors (PPIs) are medications that reduce the amount of acid secreted by cells in the lining of the stomach.
Bottom line. References. Piyapong Thongcharoen/iStock via Getty Images. Heartburn. Acid reflux. Gastroesophageal reflux disease (GERD). Chances are you’ve heard these terms used interchangeably. But they’re not quite the same thing. Heartburn is an uncomfortable, burning feeling in your chest and throat.
A pharmacists explains the difference. By Megan Nunn, PharmD. Updated on April 08, 2024. Medically reviewed by Femi Aremu, PharmD. Print. Table of Contents. View All. H2 Blockers vs PPI: How They Work. Effectiveness. How Long Do They Take To Work? Indications and Usage. Side Effects and Safety.
Updated on March 11, 2022. Key takeaways: Common types of medications to treat heartburn and gastroesophageal reflux disease (GERD) are antacids, histamine-2 antagonists (H2 blockers), and proton pump inhibitors (PPIs). Antacids and H2 blockers help treat infrequent heartburn.