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  2. Metoprolol - Wikipedia

    en.wikipedia.org/wiki/Metoprolol

    Metoprolol is used for a number of conditions, including angina, acute myocardial infarction, supraventricular tachycardia, ventricular tachycardia, congestive heart failure, and prevention of migraine headaches. [4] It is an adjunct in the treatment of hyperthyroidism. [17] Both oral and intravenous forms of metoprolol are available for administration. [18] The different salt versions of ...

  3. Sodium channel blocker - Wikipedia

    en.wikipedia.org/wiki/Sodium_channel_blocker

    They decrease conductivity, but have a minimal effect on the action potential duration. Of the sodium channel blocking antiarrhythmic agents (the class I antiarrhythmic agents), the class Ic agents have the most potent sodium channel blocking effects.

  4. Pharmacodynamics - Wikipedia

    en.wikipedia.org/wiki/Pharmacodynamics

    Pharmacodynamics (PD) is the study of the biochemical and physiologic effects of drugs (especially pharmaceutical drugs). The effects can include those manifested within animals (including humans), microorganisms, or combinations of organisms (for example, infection). Pharmacodynamics and pharmacokinetics are the main branches of pharmacology ...

  5. Grapefruit–drug interactions - Wikipedia

    en.wikipedia.org/wiki/Grapefruit–drug_interactions

    Grapefruit–drug interactions that affect the pre-systemic metabolism (i.e., the metabolism that occurs before the drug enters the blood) of drugs have a different duration of action than interactions that work by other mechanisms, such as on absorption, discussed below. [19] The interaction is greatest when the juice is ingested with the drug or up to 4 hours before the drug. [1][5][29] The ...

  6. Elimination rate constant - Wikipedia

    en.wikipedia.org/wiki/Elimination_rate_constant

    Elimination rate constant. The elimination rate constant K or Ke is a value used in pharmacokinetics to describe the rate at which a drug is removed from the human system. [1] It is often abbreviated K or Ke. It is equivalent to the fraction of a substance that is removed per unit time measured at any particular instant and has units of T −1.

  7. Beta blocker - Wikipedia

    en.wikipedia.org/wiki/Beta_blocker

    Although beta blockers were once contraindicated in congestive heart failure, as they have the potential to worsen the condition due to their effect of decreasing cardiac contractility, studies in the late 1990s showed their efficacy at reducing morbidity and mortality. [14][15][16] Bisoprolol, carvedilol, and sustained-release metoprolol are specifically indicated as adjuncts to standard ACE ...

  8. Landiolol - Wikipedia

    en.wikipedia.org/wiki/Landiolol

    Landiolol. Landiolol (INN) is an ultra short-acting, β1-superselective intravenous adrenergic antagonist, which decreases the heart rate effectively with less negative effect on blood pressure or myocardial contractility. [6][7] In comparison to other beta blockers, landiolol has the shortest elimination half-life (3 to 4 minutes), ultra-rapid ...

  9. Timolol - Wikipedia

    en.wikipedia.org/wiki/Timolol

    Timolol is a beta blocker medication used either by mouth or as eye drops. [3][5] As eye drops it is used to treat increased pressure inside the eye such as in ocular hypertension and glaucoma. [3] By mouth it is used for high blood pressure, chest pain due to insufficient blood flow to the heart, to prevent further complications after a heart ...

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