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The amygdala, cerebellum, and many other brain regions have been implicated in autism. [15]Unlike some brain disorders which have clear molecular hallmarks that can be observed in every affected individual, such as Alzheimer's disease or Parkinson's disease, autism does not have a unifying mechanism at the molecular, cellular, or systems level.
Iryna Spodarenko / GettyWe’ve come a long way in our understanding of autism since it was first used as a clinical description in 1943. Scientists have identified some of the genes that seem to ...
Human brain in the coronal orientation. Amygdalae are shown in dark red. The amygdala (/ ə ˈ m ɪ ɡ d ə l ə /; pl.: amygdalae / ə ˈ m ɪ ɡ d ə l i,-l aɪ / or amygdalas; also corpus amygdaloideum; Latin from Greek, ἀμυγδαλή, amygdalē, 'almond', 'tonsil' [1]) is a paired nuclear complex present in the cerebral hemispheres of vertebrates.
Brain sections and how autism relates to them. Many causes of autism, including environmental and genetic factors, have been recognized or proposed, but understanding of the theory of causation of autism is incomplete. [1] Attempts have been made to incorporate the known genetic and environmental causes into a comprehensive causative framework. [2]
A further example of brain structures relating to ASD is that children with ASD tend to have a larger amygdala, [47] this is another example of being an extreme version of the male brain which generally has a larger amygdala. [4] These brain differences have all been shown to have an influence on social cognition and communication.
Autism, or autism spectrum disorder [a] (ASD), is a neurodevelopmental disorder characterized by repetitive, restricted, and inflexible patterns of behavior, interests, and activities, as well as deficits in social communication and social interaction, and the presence of high or low sensory sensitivity.
Classic autism, also known as childhood autism, autistic disorder, (early) infantile autism, infantile psychosis, Kanner's autism, Kanner's syndrome, or (formerly) just autism, is a neurodevelopmental condition first described by Leo Kanner in 1943. It is characterized by atypical and impaired development in social interaction and communication ...
The following chapters investigate the biological background of autism and how historically it was claimed to be either the result of direct brain damage or poor parenting and how the practice of diagnostic classification, or nosology, negatively impacted the understanding of children with autism and others on the spectrum.