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Acutely, repletion with 10 mEq of potassium is typically expected to raise serum potassium by 0.1 mEq/L immediately after administration. However, for those with chronic hypokalemia, repletion takes time due to tissue redistribution. For example, correction by 1 mEq/L can take more than 1000 mEq of potassium over many days. [6]
Because of the risk of small-bowel lesions, the US Food and Drug Administration (FDA) requires some potassium salts containing more than 99 mg (about 1.3 mEq) to be labeled with a warning, [14] while recommending an adult daily intake of 4700 mg (about 63 mEq).
Potassium (K) – per day: 40 [5] 90 [5] mmol / 24 h: Urine K may be measured in a diagnostic examination for hypokalemia (low blood potassium). If potassium is being lost through the kidneys, urine potassium will likely be high. If urine potassium is low, this suggests a non-renal cause. [7] Urinary calcium (Ca) – per day: 2.5: 6.25: mmol / 24 h
Potassium resides mainly inside the cells of the body, so its concentration in the blood can range anywhere from 3.5 mEq/L to 5 mEq/L. [14] The kidneys are responsible for excreting the majority of potassium from the body. [14] This means their function is crucial for maintaining a proper balance of potassium in the blood stream.
Potassium chloride (KCl, or potassium salt) is a metal halide salt composed of potassium and chlorine. It is odorless and has a white or colorless vitreous crystal appearance. The solid dissolves readily in water, and its solutions have a salt-like taste. Potassium chloride can be obtained from ancient dried lake deposits. [7]
For U.S. food and dietary supplement labeling purposes, the amount in a serving is expressed as a percent of Daily Value (%DV). For potassium labeling purposes, 100% of the Daily Value was 3500 mg, but as of May 2016, it has been revised to 4700 mg. [29] [30] A table of the old and new adult Daily Values is provided at Reference Daily Intake.
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Once potassium levels have been verified to be greater than 3.3 mEq/L, then an insulin infusion of 0.1 units/kg/hr is started. [14] The goal for resolution is a blood glucose of less than 200 mg/dL. [6]
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