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Serotonin syndrome (SS) is a group of symptoms that may occur with the use of certain serotonergic medications or drugs. [1] The symptoms can range from mild to severe, and are potentially fatal. [ 4 ] [ 5 ] [ 2 ] Symptoms in mild cases include high blood pressure and a fast heart rate ; usually without a fever . [ 2 ]
Serotonin syndrome is typically caused by the use of two or more serotonergic drugs, including SSRIs. [112] Serotonin syndrome is a condition that can range from mild (most common) to deadly. Mild symptoms may consist of increased heart rate , fever , shivering, sweating , dilated pupils , myoclonus (intermittent jerking or twitching), as well ...
Extremely high levels of serotonin or activation of certain serotonin receptors can cause a condition known as serotonin syndrome, with toxic and potentially fatal effects. In practice, such toxic levels are essentially impossible to reach through an overdose of a single antidepressant drug, but require a combination of serotonergic agents ...
Serotonin syndrome can be caused by taking multiple serotonergic drugs, such as SSRIs or SNRIs. Other drugs that contribute to serotonin syndrome include MAO inhibitors, linezolid, tedizolid, methylene blue, procarbazine, amphetamines, clomipramine, and more. [ 74 ]
Lithium toxicity can be mistaken for other syndromes associated with antipsychotic use, such as serotonin syndrome because lithium increases serotonin metabolites in the cerebrospinal fluid. [14] There are several drug interactions with lithium. Interactions can occur from typical antipsychotics or atypical antipsychotics. In particular ...
“GLP-1 medications impact all of the neurotransmitters in the brain associated with mental health—norepinephrine, serotonin, and dopamine,” says Sue Decotiis, MD, a weight loss doctor based ...
NHS figures show that the number of people in England taking antidepressants continues to rise, with 8.3m patients receiving them in 2021/22.
Avoid using harmful substances: Things like smoking cigarettes and drinking alcohol can cause a drop in serotonin, Viswanathan says. Avoiding them entirely would be the most beneficial, but ...