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  2. Metformin - Wikipedia

    en.wikipedia.org/wiki/Metformin

    Activation of AMPK was required for metformin's inhibitory effect on liver glucose production. [112] AMPK is an enzyme that plays an important role in insulin signaling, whole-body energy balance, and the metabolism of glucose and fats. [113]

  3. AMP-activated protein kinase - Wikipedia

    en.wikipedia.org/wiki/AMP-activated_protein_kinase

    A second AMPK-control system [66] localized to lysosomes depends on the Galectin-9-TAK1 system and ubiquitination responses at controlled by deubiquitinating enzymes such as USP9X leading to AMPK activation in response to lysosomal damage, [66] a condition that can occur biochemically, physically via protein aggregates such as proteopathic tau ...

  4. 6 Benefits of Taking Metformin (Besides Weight Loss) - AOL

    www.aol.com/lifestyle/6-benefits-taking...

    2. Alleviates Hunger. Metformin improves how well your cells respond to insulin. This helps regulate your blood sugar levels and manage spikes in insulin that can trigger hunger and food cravings.

  5. Diabetes medication - Wikipedia

    en.wikipedia.org/wiki/Diabetes_medication

    Metformin is a first-line medication used for treatment of type 2 diabetes. It is generally prescribed at initial diagnosis in conjunction with exercise and weight loss, as opposed to the past, where it was prescribed after diet and exercise had failed.

  6. 4 Tips for Knowing When to Take Metformin - AOL

    www.aol.com/4-tips-knowing-metformin-145100341.html

    Whether you’re taking metformin for weight loss, type 2 diabetes, prediabetes, polycystic ovary syndrome (PCOS), or another medical condition entirely, you want to get the most out of your ...

  7. Galectin-9 - Wikipedia

    en.wikipedia.org/wiki/Galectin-9

    Galectin-9, through its cytoplasmic action in control of AMPK, [11] [12] may affect various health conditions impacted by AMPK, including metabolism, obesity, diabetes, cancer, immune responses, and may be a part of the mechanism of action of the widely-prescribed anti-diabetes drug metformin. [12]

  8. Metabolic dysfunction–associated steatotic liver disease

    en.wikipedia.org/wiki/Metabolic_dysfunction...

    The condition is strongly associated with or caused by type 2 diabetes, insulin resistance, and metabolic syndrome (defined as at least three of the five following medical conditions: abdominal obesity, high blood pressure, high blood sugar, high serum triglycerides, and low serum high-density lipoprotein).

  9. Biomarkers of diabetes - Wikipedia

    en.wikipedia.org/wiki/Biomarkers_of_diabetes

    Gestational diabetes is a condition in which a woman without diabetes develops high blood sugar levels during pregnancy. [ 4 ] Type 2 diabetes mellitus and prediabetes are associated with changes in levels of metabolic markers, these markers could serve as potential prognostic or therapeutic targets for patients with prediabetes or Type 2 ...

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