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Carcinoembryonic antigen (CEA) describes a set of highly-related glycoproteins involved in cell adhesion. CEA is normally produced in gastrointestinal tissue during fetal development, but the production stops before birth. Consequently, CEA is usually present at very low levels in the blood of healthy adults (about 2–4 ng/mL). [2]
In the literature, CEACAM5 is often used as a synonym for cancer embryonic antigen (CEA), a well-known biomarker of many types of malignancies, such as colorectal cancer and non-small-cell lung cancer. [4] [5] Its primary function in the embryonic intestine and colon tumors is adhesion between epithelial cells. [6]
Tumor markers may be used for the following purposes: Monitoring the malignancy; When a malignant tumor is found by the presence of a tumor marker, the level of marker found in the body can be monitored to determine the state of the tumor and how it responds to treatment. If the quantity stays the same during treatment it can indicate that the ...
A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule." [18] In cancer research and medicine, biomarkers are used in three primary ways: [19] To help diagnose conditions, as in the case of identifying early stage cancers (diagnostic)
Colorectal cancer (CRC), also known as bowel cancer, colon cancer, or rectal cancer, is the development of cancer from the colon or rectum (parts of the large intestine). [5] Signs and symptoms may include blood in the stool , a change in bowel movements , weight loss, abdominal pain and fatigue. [ 9 ]
n/a Ensembl ENSG00000124469 n/a UniProt P31997 n/a RefSeq (mRNA) NM_001816 n/a RefSeq (protein) NP_001807 n/a Location (UCSC) Chr 19: 42.58 – 42.6 Mb n/a PubMed search n/a Wikidata View/Edit Human Carcinoembryonic antigen-related cell adhesion molecule 8 (CEACAM8) also known as CD66b (C luster of D ifferentiation 66b), is a member of the carcinoembryonic antigen (CEA) gene family. Its main ...
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