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  2. Cytokine release syndrome - Wikipedia

    en.wikipedia.org/wiki/Cytokine_release_syndrome

    Patients with fulminant COVID-19 and ARDS have classical serum biomarkers of CRS including elevated CRP, LDH, IL-6, and ferritin. [ 17 ] Hemophagocytic lymphohistiocytosis and Epstein-Barr virus-related hemophagocytic lymphohistiocytosis are caused by extreme elevations in cytokines and can be regarded as one form of severe cytokine release ...

  3. Cytokine storm - Wikipedia

    en.wikipedia.org/wiki/Cytokine_storm

    Ferritin and C-reactive protein may be possible screening tools for early diagnosis of systemic inflammatory response syndrome in cases of COVID-19. [31] Due to the increased levels of cytokines and interferons in patients with severe COVID-19, both have been investigated as potential targets for SARS-CoV-2 therapy.

  4. C-reactive protein - Wikipedia

    en.wikipedia.org/wiki/C-reactive_protein

    [citation needed] Other inflammatory mediators that can increase CRP are TGF beta 1, and tumor necrosis factor alpha. In acute inflammation, CRP can increase as much as 50 to 100 mg/L within 4 to 6 hours in mild to moderate inflammation or an insult such as skin infection, cystitis, or bronchitis [clarification needed]. It can double every 8 ...

  5. Treatment and management of COVID-19 - Wikipedia

    en.wikipedia.org/wiki/Treatment_and_management...

    This registry based, multi-center, multi-country data provide provisional support for the use of ECMO for COVID-19 associated acute hypoxemic respiratory failure. Given that this is a complex technology that can be resource intense, guidelines exist for the use of ECMO during the COVID-19 pandemic. [85] [86] [87]

  6. Multisystem inflammatory syndrome in children - Wikipedia

    en.wikipedia.org/wiki/Multisystem_inflammatory...

    such as ESR, C-reactive protein, or procalcitonin; And. No other obvious microbial cause of inflammation, including bacterial sepsis, staphylococcal or streptococcal shock syndromes; And. Evidence of COVID-19 (RT-PCR, antigen test or serology positive), or likely contact with patients with COVID-19 (Note: Consider this syndrome in children with ...

  7. Acute-phase protein - Wikipedia

    en.wikipedia.org/wiki/Acute-phase_protein

    In contrast, C-reactive protein (with a half-life of 6–8 hours) rises rapidly and can quickly return to within the normal range if treatment is employed. For example, in active systemic lupus erythematosus, one may find a raised ESR but normal C-reactive protein. [citation needed] They may also indicate liver failure. [11]

  8. Inflammatory cytokine - Wikipedia

    en.wikipedia.org/wiki/Inflammatory_cytokine

    With such a strong inflammatory response and an elevated number of immune cells, lungs of cystic fibrosis patients cannot clear the bacteria and become more susceptible to infections. A high prevalence (40-70%) of patients with cystic fibrosis show signs of asthma , possibly due to the primary deficiency in the cystic fibrosis transmembrane ...

  9. Immunosuppressive drug - Wikipedia

    en.wikipedia.org/wiki/Immunosuppressive_drug

    The patient has fever, joint pain, and erythema that can be soothed with the use of steroids and analgesics. Urticaria (hives) can also be present. It is possible to diminish their toxicity by using highly purified serum fractions and intravenous administration in the combination with other immunosuppressants, for example, calcineurin ...