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Lifespan debuted at #11 on The New York Times hardcover nonfiction bestseller list on September 28, 2019. [1]The book received mixed reviews from critics. "If you're even mildly hopeful about dunking a basketball at the age of 50, or hiking the Appalachian Trail at 70, or blowing 100 candles out on your birthday cake someday, you might consider making room for Lifespan on your bookshelf," one ...
David Andrew Sinclair AO (born June 26, 1969) is an Australian-American biologist and academic known for his research on aging and epigenetics. Sinclair is a professor of genetics at Harvard Medical School and the founding director of the Paul F. Glenn Laboratories for the Biological Mechanisms of Aging at Harvard.
Sirtris Pharmaceuticals, Inc. was a biotechnology company based in Cambridge, MA that developed therapies for type 2 diabetes, cancer, and other diseases. Conceived in 2004 by Harvard University biologist David Sinclair and Andrew Perlman, [1] and founded that year by Sinclair and Perlman, along with Christoph Westphal, Richard Aldrich, Richard Pops, and Paul Schimmel, [2] the company was ...
In 2003, Aubrey de Grey and David Gobel formed the Methuselah Foundation, which gives financial grants to anti-aging research projects. In 2009, de Grey and several others founded the SENS Research Foundation , a California-based scientific research organization which conducts research into aging and funds other anti-aging research projects at ...
An anti-ageing influencer who claims to have knocked 24 years off his internal age has revealed the secrets of his ultra-healthy regime.. Dave Pascoe, 61, claims to have reversed his biological ...
In 1991 his lab started to study genes involved in aging. [5] In 1993, Cynthia Kenyon's lab at UCSF discovered that a single-gene mutation in could double the lifespan of C. elegans. That same year, David Sinclair joined the Guarente lab, and they developed the hypothesis that caloric restriction slows aging by activation of sirtuins. [8]
In January, a team led by David Sinclair shows in a 13-year-long international study how DNA breaks or epigenetic damage are a major driver of epigenetic change, and how the loss of epigenetic information is a cause of aging in mammals. It concluded that the loss of epigenetic information can drive aging independently of changes to the genetic ...
Considered the original anti-suburban novel, "Revolutionary Road" follows a young, bright couple marooned in Connecticut and trying to escape pressure to conform in the 1950s.
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