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Memantine has been studied and used off-label in the treatment of a variety of psychiatric disorders. [68] These include depression, bipolar disorder, schizophrenia, obsessive–compulsive disorder (OCD), substance misuse, pervasive developmental disorders (PDDs), and binge eating disorder (BED). [68]
It is often used off-label as a nootropic. Prazosin (Minipress) for nightmares: prazosin is approved for the use of hypertension. A 2012 systematic review showed a small benefit for the treatment of PTSD-associated night terrors. Other non-FDA-approved uses for prazosin include the treatment of Raynaud's disease and poisoning due to scorpion venom.
Off-label use is the use of pharmaceutical drugs for an unapproved indication or in an unapproved age group, dosage, or route of administration. [1] Both prescription drugs and over-the-counter drugs (OTCs) can be used in off-label ways, although most studies of off-label use focus on prescription drugs.
While estimates vary, some studies suggest that 1 in 5 prescriptions of common medications involves an off-label use. Skip to main content. 24/7 Help. For premium support please call: 800-290 ...
Used off-label to treat insomnia; Sonata – a non-benzodiazepine hypnotic; Spravato – a rapid-acting antidepressant of the NMDA receptor antagonist class; enantiomer of ketamine; Stelazine (trifluoperazine) – an antipsychotic used in the treatment of psychotic disorders, anxiety, and nausea caused by chemotherapy [2]
In addition to these FDA-approved uses, Tedeschi says gabapentin is also sometimes prescribed off-label by providers for a variety of other medical conditions. (Off-label use means evidence exists ...
Memantine (Namenda) – ionotropic glutamate NMDA receptor antagonist, other actions [87] Oxytocin intranasal (Syntocinon Nasal Spray; TUR 001) – oxytocin receptor agonist [88] Research programme: AMPA receptor agonists (ampakines, AMPAkines; CX compounds) - RespireRx – ionotropic glutamate AMPA receptor agonists [89]
Chlorpromazine is occasionally used off-label for treatment of severe migraine. [19] [20] It is often, particularly as palliation, used in small doses to reduce nausea by opioid-treated cancer patients and to intensify and prolong the analgesia of the opioids as well. [19] [21] Efficacy has been shown in treatment of symptomatic hypertensive ...