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Actinomycosis is a rare infectious bacterial disease caused by the gram-positive Actinomyces species. [1] The name refers to ray-like appearance of the organisms in the granules. About 70% of infections are due to either Actinomyces israelii or A. gerencseriae. [1] Infection can also be caused by Streptomyces somaliensis and Propionibacterium ...
Actinomyces is a genus of the Actinomycetia class of bacteria. They all are Gram-positive and facultatively anaerobic , growing best under anaerobic conditions. [ 2 ] Actinomyces species may form endospores , and while individual bacteria are rod-shaped , Actinomyces colonies form fungus -like branched networks of hyphae . [ 3 ]
Actinomyces and its associated species have, for a long time, been implicated in human infections, particularly those of the mouth, pharynx, distal esophagus, and genitourinary tract. [9] Within the last 10 years, A. massiliensis has been detected in blood, and most Actinomyces bacteremias stem from oral sources. [ 9 ]
Scanning electron micrograph of Actinomyces israelii. Scientific classification; Domain: Bacteria: Phylum: Actinomycetota: Class: Actinomycetia (Stackebrandt et al. 1997) Salam et al. 2020 [1] Type genus; Actinomyces
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Actinomycosis is most frequently caused by A. israelii. [4] It is a normal colonizer of the vagina, [5] colon, and mouth. [6] Infection is established first by a breach of the mucosal barrier during various procedures (dental, gastrointestinal), aspiration, or pathologies such as diverticulitis. [7]
Actinomycetales can be found mostly in soil and decaying organic matter, as well as in living organisms such as humans and animals. They form symbiotic nitrogen fixing associations with over 200 species of plants, and can also serve as growth promoting or biocontrol agents, or cause disease in some species of plants.
The Actinomycetaceae (often called actinomycetes or mycelial bacteria) are a family of bacteria in the order Actinomycetales that contains the medically important genus Actinomyces. These organisms are closely related to the mycobacteria, but were originally classified as fungi because they were thought to be transitional forms between bacteria ...