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Outside the range of pH that is compatible with life, proteins are denatured and digested, enzymes lose their ability to function, and the body is unable to sustain itself. The kidneys maintain acid-base homeostasis by regulating the pH of the blood plasma. Gains and losses of acid and base must be balanced.
Renal compensation is a mechanism by which the kidneys can regulate the plasma pH. It is slower than respiratory compensation, but has a greater ability to restore normal values. Kidneys maintain the acid-base balance through two mechanisms: (1) the secretion of H + ions into the urine (from the blood) and (2) the reabsorption of bicarbonate ...
The kidneys can be unilobar (a single lobe represented by a single renal pyramid) or multilobar, [13] [14] unipapillary (a single or a common papilla), with several papillae or multipapillary, [14] [15] may be smooth-surfaced or lobulated. [1] [13] The multilobar kidneys can also be reniculate, which are found mainly in marine mammals. [16]
The kidneys are a pair of organs of the excretory system in vertebrates, which maintain the balance of water and electrolytes in the body (osmoregulation), filter the blood, remove metabolic waste products, and, in many vertebrates, also produce hormones (in particular, renin) and maintain blood pressure.
The two organ systems that help regulate the body's acid–base balance are the kidneys and lungs. Acid–base homeostasis is the maintenance of pH around a value of 7.4. The lungs are the part of respiratory system which helps to maintain acid–base homeostasis by regulating carbon dioxide (CO 2) concentration in the blood. The respiratory ...
Maintain pH and osmotic concentration of the extracellular fluid. Excrete toxic metabolic by-products such as urea, ammonia, and uric acid. The way the kidneys do this is with nephrons. There are over 1 million nephrons in each kidney; these nephrons act as filters inside the kidneys. The kidneys filter needed materials and waste.
Each of these variables is controlled by one or more regulators or homeostatic mechanisms, which together maintain life. Homeostasis is brought about by a natural resistance to change when already in optimal conditions, [2] and equilibrium is maintained by many regulatory mechanisms; it is thought to be the central motivation for all organic ...
The kidney maintains the electrolyte concentrations, osmolality, and acid-base balance of blood plasma within the narrow limits that are compatible with effective cellular function; and the kidney participates in blood pressure regulation and in the maintenance of steady whole-organism water volume [4]