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The variation has led to the suggestion that treatment responsive and treatment resistant schizophrenia be considered as two different subtypes. [ 149 ] [ 159 ] It is further suggested that if the subtypes could be distinguished at an early stage significant implications could follow for treatment considerations, and for research. [ 154 ]
Clozapine is an effective treatment for those who respond poorly to other drugs ("treatment-resistant" or "refractory" schizophrenia), [94] but it has the potentially serious side effect of agranulocytosis (lowered white blood cell count) in less than 4% of people. [95]
Saphris – atypical antipsychotic used to treat schizophrenia and bipolar disorder; Serax – anti-anxiety medication of the benzodiazepine class, often used to help during detoxification from alcohol or other addictive substances; Serentil (mesoridazine) – an antipsychotic drug used in the treatment of schizophrenia [1]
The Texas Medication Algorithm Project (TMAP) [1] is a decision-tree medical algorithm, the design of which was based on the expert opinions of mental health specialists.It has provided and rolled out a set of psychiatric management guidelines for doctors treating certain mental disorders within Texas' publicly funded mental health care system, along with manuals relating to each of them The ...
The primary treatment of schizophrenia is the use of antipsychotic medications, often in combination with psychosocial interventions and social supports. [ 27 ] [ 185 ] Community support services including drop-in centers, visits by members of a community mental health team , supported employment , [ 186 ] and support groups are common.
Clozapine — used in treatment-resistant schizophrenia not responsive to at least two different antipsychotics; the main reason for such restriction is agranulocytosis and other severe side effects including seizures and myocarditis. [10] Felbamate — an anticonvulsant used in refractory epilepsy.
ECT is used, where possible, with informed consent [33] in treatment-resistant major depressive disorder, bipolar depression, treatment-resistant catatonia, prolonged or severe mania, and in conditions where "there is a need for rapid, definitive response because of the severity of a psychiatric or medical condition (e.g., when illness is ...
Though not approved for treatment use by the FDA, research suggests that Clozapine may also be effective in treating schizoaffective disorder, particularly in those resistant to initial medication. [82] Clozapine is an atypical antipsychotic that is recognized as being particularly effective when other antipsychotic agents have failed. [83]
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