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  3. Trifluoromethylation - Wikipedia

    en.wikipedia.org/wiki/Trifluoromethylation

    The challenges associated with observation of CF 3 anion are alluded to its strong basic nature and its tendency to form pentacoordinated silicon species, such as [Me 3 Si(CF 3) 2] − or [Me 3 Si(F)(CF 3)] −. The reactivity of fluoroform in combination with a strong base such as t-BuOK with carbonyl compounds in DMF is an example. [54]

  4. Trifluoromethyltrimethylsilane - Wikipedia

    en.wikipedia.org/wiki/Trifluoromethyltrimethylsilane

    Trifluoromethyltrimethylsilane (known as Ruppert-Prakash reagent, TMSCF 3) is an organosilicon compound with the formula CF 3 Si(CH 3) 3.It is a colorless liquid. The compound is a reagent used in organic chemistry for the introduction of the trifluoromethyl group.

  5. Trifluoromethanesulfonyl azide - Wikipedia

    en.wikipedia.org/wiki/Trifluoromethanesulfonyl_azide

    Trifluoromethanesulfonyl azide is prepared by treating trifluoromethanesulfonic anhydride with sodium azide, traditionally in dichloromethane. [1] However, the use of dichloromethane is avoided since it can generate highly explosive azido-chloromethane and diazidomethane.

  6. Trifluoromethanol - Wikipedia

    en.wikipedia.org/wiki/Trifluoromethanol

    Colorless liquid Density: 1.5±0.1 g/cm 3: ... trifluoromethanol can be prepared from trifluoromethyl hypochlorite and ... in an aqueous solution displaced by an acid ...

  7. Trifluoromethyl group - Wikipedia

    en.wikipedia.org/wiki/Trifluoromethyl_group

    Trifluoromethyl group covalently bonded to an R group. The trifluoromethyl group is a functional group that has the formula-CF 3. The naming of is group is derived from the methyl group (which has the formula -CH 3), by replacing each hydrogen atom by a fluorine atom. Some common examples are trifluoromethane H– CF 3, 1,1,1-trifluoroethane H ...

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  9. Topical cream formulation - Wikipedia

    en.wikipedia.org/wiki/Topical_cream_formulation

    Topical cream formulation is an emulsion semisolid dosage form that is used for skin external application. Most of the topical cream formulations contain more than 20 per cent of water and volatiles and/or less than 50 per cent of hydrocarbons , waxes , or polyethylene glycols as the vehicle for external skin application. [ 1 ]

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