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Trihexyphenidyl is used for the symptomatic treatment of Parkinson's disease in mono and combination therapy. [5] It is active in postencephalitic, arteriosclerotic, and idiopathic forms. The drug is also commonly used to treat extrapyramidal side effects occurring during antipsychotic treatment.
Parkinson's Disease causes constipation and gastric dysmotility that is severe enough to endanger comfort and even health. [26] A factor in this is the appearance of Lewy bodies and Lewy neurites even before these affect the functioning of the substantia nigra in the neurons in the enteric nervous system that control gut functions.
In the management of Parkinson's disease, due to the chronic nature of Parkinson's disease (PD), a broad-based program is needed that includes patient and family education, support-group services, general wellness maintenance, exercise, and nutrition. At present, no cure for the disease is known, but medications or surgery can provide relief ...
The Michael J. Fox Foundation, which he founded in 2000, has raised over $2 billion for Parkinson's research. [285] Boxer Muhammad Ali showed signs of PD when he was 38, but was undiagnosed until he was 42; he has been called the "world's most famous Parkinson's patient". [286] Whether he had PD or parkinsonism related to boxing is unresolved ...
Carbidopa/levodopa, also known as levocarb and co-careldopa, is the combination of the two medications carbidopa and levodopa. [6] It is primarily used to manage the symptoms of Parkinson's disease, but it does not slow down the disease or stop it from getting worse. [6]
The side effects of nicergoline are usually limited to nausea, hot flushes, mild gastric upset, hypotension and dizziness. [6] At high drug dosages, bradycardia, increased appetite, agitation, diarrhea and perspiration were reported. Most of the available literature suggests that the side effects of nicergoline are mild and transient. [2]
Treatment of Parkinson's disease (PD), either as monotherapy (without levodopa) or in combination with L-DOPA therapy, in the early stages of the disease as well as in the advanced ones; Treatment of pathological cognitive deficits in the elderly (impaired attention, motivation, memory, etc.) Treatment of dizziness in the young patients
Drug-induced arrhythmia worsened by anticholinergics' side effect of tachycardia. Parkinson's disease, e.g. levodopa. Atropine decreases the absorption of levodopa. Preventing travel sickness, relieve stomach cramps or spasms, e.g. hyoscine. Additive effect. Nausea and vomiting, e.g. cyclizine. Additive effect.