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Lobes in this cortex are more closely associated with memory and in particular autobiographical memory. [15] The temporal lobes are also concerned with recognition memory. This is the capacity to identify an item as one that was recently encountered. [16] Recognition memory is widely viewed as consisting of two components, a familiarity ...
Historically, questions regarding the functional architecture of the mind have been divided into two different theories of the nature of the faculties. The first can be characterized as a horizontal view because it refers to mental processes as if they are interactions between faculties such as memory, imagination, judgement, and perception, which are not domain specific (e.g., a judgement ...
While the basis of the mechanism among cellular memory modules is the same, what initiates the mechanism and the specific proteins carrying it out differ based on the location of the cellular memory module within the gene. Some of these specific mechanisms and gene locations have been analyzed from experiments and outlined below.
Hering and Semon developed general theories of memory, the latter inventing the idea of the engram and concomitant processes of engraphy and ecphory. Semon divided memory into genetic memory and central nervous memory. [7] This 19th-century view is not wholly dead, albeit that it stands in stark contrast to the ideas of neo-Darwinism. In modern ...
HAR1F is active in the developing human brain. The HAR1 sequence is found (and conserved) in chickens and chimpanzees but is not present in fish or frogs that have been studied. There are 18 base pair mutations different between humans and chimpanzees, far more than expected by its history of conservation. [1]
Knockout studies in Aplysia sea slugs indicated that decreasing CREB function blocks long-term changes in synaptic function, but not short-term ones. [3] Changes in synaptic function (i.e., synaptic plasticity) are required for learning and memory [4] As evidence of this, a line of mice with a targeted disruption of the α and δ isoforms of CREB showed intact short-term memory, but disrupted ...
Neuromodulation is the physiological process by which a given neuron uses one or more chemicals to regulate diverse populations of neurons. Neuromodulators typically bind to metabotropic, G-protein coupled receptors (GPCRs) to initiate a second messenger signaling cascade that induces a broad, long-lasting signal.
Cis-regulatory elements (CREs) or cis-regulatory modules (CRMs) are regions of non-coding DNA which regulate the transcription of neighboring genes.CREs are vital components of genetic regulatory networks, which in turn control morphogenesis, the development of anatomy, and other aspects of embryonic development, studied in evolutionary developmental biology.