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The muscarinic acetylcholine receptor M 1, also known as the cholinergic receptor, muscarinic 1, is a muscarinic receptor that in humans is encoded by the CHRM1 gene. [5] It is localized to 11q13. [5] This receptor is found mediating slow EPSP at the ganglion in the postganglionic nerve, [6] is common in exocrine glands and in the CNS. [7] [8]
A muscarinic acetylcholine receptor agonist, also simply known as a muscarinic agonist or as a muscarinic agent, is an agent that activates the activity of the muscarinic acetylcholine receptor. [1] The muscarinic receptor has different subtypes, labelled M1-M5, allowing for further differentiation.
Meanwhile, geneticists and molecular biologists have characterised five genes that appear to encode muscarinic receptors, named m1-m5 (lowercase m; no subscript number). They code for pharmacologic types M 1-M 5. The receptors m1 and m2 were determined based upon partial sequencing of M 1 and M 2 receptor proteins.
The muscarinic acetylcholine receptor M 2, also known as the cholinergic receptor, muscarinic 2, is a muscarinic acetylcholine receptor that in humans is encoded by the CHRM2 gene. [5] Multiple alternatively spliced transcript variants have been described for this gene. [5] It is G i-coupled, reducing intracellular levels of cAMP.
Pages in category "M1 receptor agonists" The following 25 pages are in this category, out of 25 total. This list may not reflect recent changes. 0–9. 77-LH-28-1; A.
Xanomeline is an agonist that primarily targets the muscarinic acetylcholine receptor family of five muscarinic receptor subtypes, which are designated M 1-M 5. [2] While it binds with near identical affinity to all five of the muscarinic receptor subtypes as measured by displacement of a muscarinic radioligand, the preponderance of evidence suggests that xanomeline acts preferentially in the ...
M1 receptor agonists (25 P) M2 receptor agonists (15 P) ... M4 receptor positive allosteric modulators (4 P) M5 receptor agonists (12 P)
Pages in category "M2 receptor agonists" The following 15 pages are in this category, out of 15 total. This list may not reflect recent changes. A. Aceclidine;